Three amino acids in the D2 dopamine receptor regulate selective ligand function and affinity.
about
Transmembrane segment five serines of the D4 dopamine receptor uniquely influence the interactions of dopamine, norepinephrine, and Ro10-4548.Design, synthesis, radiolabeling, and in vivo evaluation of carbon-11 labeled N-[2-[4-(3-cyanopyridin-2-yl)piperazin-1-yl]ethyl]-3-methoxybenzamide, a potential positron emission tomography tracer for the dopamine D(4) receptorsPharmGKB summary: dopamine receptor D2Ring substituents on substituted benzamide ligands indirectly mediate interactions with position 7.39 of transmembrane helix 7 of the D4 dopamine receptor.Modeling loop backbone flexibility in receptor-ligand docking simulations.
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Three amino acids in the D2 dopamine receptor regulate selective ligand function and affinity.
description
2009 nî lūn-bûn
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Three amino acids in the D2 do ...... ligand function and affinity.
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Three amino acids in the D2 do ...... ligand function and affinity.
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Three amino acids in the D2 do ...... ligand function and affinity.
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Three amino acids in the D2 do ...... ligand function and affinity.
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Three amino acids in the D2 do ...... ligand function and affinity.
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Three amino acids in the D2 do ...... ligand function and affinity.
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P2860
P1476
Three amino acids in the D2 do ...... e ligand function and affinity
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David F Cummings
John A Schetz
P2860
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10.1111/J.1471-4159.2009.06103.X
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P577
2009-04-16T00:00:00Z