Differential modulation of farnesoid X receptor signaling pathway by the thiazolidinediones
about
Estrogen and Estrogen Receptor-α-Mediated Transrepression of Bile Salt Export PumpFXR signaling in the enterohepatic systemMechanistic insights into isoform-dependent and species-specific regulation of bile salt export pump by farnesoid X receptor.Bile salt export pump is dysregulated with altered farnesoid X receptor isoform expression in patients with hepatocellular carcinomaClinical application of transcriptional activators of bile salt transporters.Pleiotropic functions of the organic solute transporter Ostα-Ostβ.Scoparone potentiates transactivation of the bile salt export pump gene and this effect is enhanced by cytochrome P450 metabolism but abolished by a PKC inhibitor.Synthesis and biological evaluations of chalcones, flavones and chromenes as farnesoid x receptor (FXR) antagonists.Intrahepatic cholestasis of pregnancy levels of sulfated progesterone metabolites inhibit farnesoid X receptor resulting in a cholestatic phenotypeThe role of bile salt export pump gene repression in drug-induced cholestatic liver toxicity.Validation of precision-cut liver slices to study drug-induced cholestasis: a transcriptomics approach.Farnesoid x receptor agonists: what they are and how they might be used in treating liver disease.Medicinal chemistry of farnesoid X receptor ligands: from agonists and antagonists to modulators.Design, Synthesis, and Biological Evaluation of Novel Nonsteroidal Farnesoid X Receptor (FXR) Antagonists: Molecular Basis of FXR Antagonism.Antidiabetic sulfonylureas modulate farnesoid X receptor activation and target gene transcription.Monitoring bile acid transport in single living cells using a genetically encoded Förster resonance energy transfer sensor.Discovery of new non-steroidal farnesoid X receptor modulators through 3D shape similarity search and structure-based virtual screening.Early Alterations of Bile Canaliculi Dynamics and the Rho Kinase/Myosin Light Chain Kinase Pathway Are Characteristics of Drug-Induced Intrahepatic Cholestasis.
P2860
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P2860
Differential modulation of farnesoid X receptor signaling pathway by the thiazolidinediones
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Differential modulation of far ...... hway by the thiazolidinediones
@en
Differential modulation of far ...... way by the thiazolidinediones.
@nl
type
label
Differential modulation of far ...... hway by the thiazolidinediones
@en
Differential modulation of far ...... way by the thiazolidinediones.
@nl
prefLabel
Differential modulation of far ...... hway by the thiazolidinediones
@en
Differential modulation of far ...... way by the thiazolidinediones.
@nl
P2093
P2860
P356
P1476
Differential modulation of far ...... hway by the thiazolidinediones
@en
P2093
Bingfang Yan
Rajani Kaimal
Ruitang Deng
Xiulong Song
P2860
P304
P356
10.1124/JPET.109.151233
P407
P577
2009-04-15T00:00:00Z