Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent. - Test2 - elhamkhani - TriplyDB

Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent.

Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent.

http://www.wikidata.org/entity/Q39914977

about

Bile acids: regulation of apoptosis by ursodeoxycholic acid Alveolar type II epithelial cell dysfunction in rat experimental hepatopulmonary syndrome (HPS)Angiotensin II protects primary rat hepatocytes against bile salt-induced apoptosis Phosphatidylinositol-3-kinase p110γ contributes to bile salt-induced apoptosis in primary rat hepatocytes and human hepatoma cells Cystic fibrosis related liver disease--another black box in hepatology.Lithocholic acid feeding results in direct hepato-toxicity independent of neutrophil function in mice The Bile Acid Nuclear Receptor FXRα Is a Critical Regulator of Mouse Germ Cell Fate Protein kinase Cδ protects against bile acid apoptosis by suppressing proapoptotic JNK and BIM pathways in human and rat hepatocytes.Bile acid-induced necrosis in primary human hepatocytes and in patients with obstructive cholestasis.cAMP-guanine exchange factor protection from bile acid-induced hepatocyte apoptosis involves glycogen synthase kinase regulation of c-Jun NH2-terminal kinase Hydrophobic bile acid apoptosis is regulated by sphingosine-1-phosphate receptor 2 in rat hepatocytes and human hepatocellular carcinoma cells.Novel insight into mechanisms of cholestatic liver injury.Circulating FGF19 closely correlates with bile acid synthesis and cholestasis in patients with primary biliary cirrhosis.Bile Acid-Induced Toxicity in HepaRG Cells Recapitulates the Response in Primary Human Hepatocytes Role of interleukin-1 and its antagonism of hepatic stellate cell proliferation and liver fibrosis in the Abcb4(-/-) mouse model.Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO⁻₃ output Plasma biomarkers of liver injury and inflammation demonstrate a lack of apoptosis during obstructive cholestasis in mice Apoptosis and necrosis in the liver Immune-mediated liver diseases: programmed cell death ligands and circulating apoptotic markers.ATP11C targets basolateral bile salt transporter proteins in mouse central hepatocytes.Possible Involvement of Nitric Oxide in Enhanced Liver Injury and Fibrogenesis during Cholestasis in Cytoglobin-deficient Mice.Caspase-6 activity in the CA1 region of the hippocampus induces age-dependent memory impairment.Genetic variations of bile salt transporters as predisposing factors for drug-induced cholestasis, intrahepatic cholestasis of pregnancy and therapeutic response of viral hepatitis.A morphological and immunohistochemical study of the effects of prednisolone or ursodeoxycholic acid on liver histology in feline lymphocytic cholangitis.A biliary HCO3- umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes.Biliary bicarbonate secretion constitutes a protective mechanism against bile acid-induced injury in man.Lack of glycoprotein 130/signal transducer and activator of transcription 3-mediated signaling in hepatocytes enhances chronic liver injury and fibrosis progression in a model of sclerosing cholangitis.Integrative microRNA profiling in alcoholic hepatitis reveals a role for microRNA-182 in liver injury and inflammation.Identification of Caspase-6 as a New Regulator of Alternatively Activated Macrophages.Lipid raft-dependent death receptor 5 (DR5) expression and activation are critical for ursodeoxycholic acid-induced apoptosis in gastric cancer cells.Physiological hypoxia prevents bile salt-induced apoptosis in human and rat hepatocytes.Farnesoid X Receptor Signaling Activates the Hepatic X-box Binding Protein 1 Pathway in vitro and in Mice.Metabolism Exogenous exosomes from mice with acetaminophen-induced liver injury promote toxicity in the recipient hepatocytes and mice

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P2860

Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent.

http://www.wikidata.org/entity/Q39914977

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

@wuu

2008年学术文章

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2008年学术文章

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2008年学术文章

@zh-my

2008年学术文章

@zh-sg

2008年學術文章

@yue

2008年學術文章

@zh

2008年學術文章

@zh-hant

name

Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent.

@en

Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent.

@nl

type

label

Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent.

@en

Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent.

@nl

prefLabel

Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent.

@en

Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent.

@nl

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P1433

Journal of Biological Chemistry

P1476

Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent.

@en

P2093

Carina Bernt

http://www.w3.org/2001/XMLSchema#string

Christian Rust

http://www.w3.org/2001/XMLSchema#string

Nadine Wild

http://www.w3.org/2001/XMLSchema#string

Ralf Wimmer

http://www.w3.org/2001/XMLSchema#string

Timo Vennegeerts

http://www.w3.org/2001/XMLSchema#string

Ulrich Beuers

http://www.w3.org/2001/XMLSchema#string

P2860

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

Caspases: the executioners of apoptosis

Caspases: pharmacological manipulation of cell death

FADD adaptor in cancer

The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade

Caspase-6 is the direct activator of caspase-8 in the cytochrome c-induced apoptosis pathway: absolute requirement for removal of caspase-6 prodomain

Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation

Bile salt-induced apoptosis involves NADPH oxidase isoform activation

Two CD95 (APO-1/Fas) signaling pathways

Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas.

P304

2908-2916

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scholarly article

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10.1074/JBC.M804585200

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5

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284

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19017654

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P921

apoptotic process