c-Jun N-terminal kinases (JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT signaling. - Test2 - elhamkhani - TriplyDB

c-Jun N-terminal kinases (JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT signaling.

c-Jun N-terminal kinases (JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT signaling.

http://www.wikidata.org/entity/Q39927730

about

Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growth Signaling effectors underlying pathologic growth and remodeling of the heart Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale.Isogarcinol is a new immunosuppressant Regulation of Akt/PKB activity by P21-activated kinase in cardiomyocytes Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart The AP-1 transcription factor c-Jun prevents stress-imposed maladaptive remodeling of the heart.Direct and indirect interactions between calcineurin-NFAT and MEK1-extracellular signal-regulated kinase 1/2 signaling pathways regulate cardiac gene expression and cellular growth.Pathway analysis of dilated cardiomyopathy using global proteomic profiling and enrichment maps.Regulation of calcineurin through transcriptional induction of the calcineurin A beta promoter in vitro and in vivo.Crosstalk between mitogen-activated protein kinases and mitochondria in cardiac diseases: therapeutic perspectives Activity- and calcineurin-independent nuclear shuttling of NFATc1, but not NFATc3, in adult skeletal muscle fibers.c-Jun N-terminal kinase (JNK-1) confers protection against brief but not extended ischemia during acute myocardial infarction.Transfusion effects on cardiomyocyte growth and proliferation in fetal sheep after chronic anemia Succinate causes pathological cardiomyocyte hypertrophy through GPR91 activation.Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases.Re-employment of developmental transcription factors in adult heart disease GnRH regulation of Jun and Atf3 requires calcium, calcineurin, and NFAT.Orphan Nuclear Receptor Nur77 Inhibits Cardiac Hypertrophic Response to Beta-Adrenergic Stimulation.Targeting calcineurin and associated pathways in cardiac hypertrophy and failure.Lost in transgenesis: a user's guide for genetically manipulating the mouse in cardiac research.Novel roles of PAK1 in the heart.Nuclear factor of activated T cells balances angiogenesis activation and inhibition.Pathogenesis of hypertrophic cardiomyopathy caused by myozenin 2 mutations is independent of calcineurin activity Heart failure with preserved ejection fraction: chronic low-intensity interval exercise training preserves myocardial O2 balance and diastolic function.Disease mechanisms and emerging therapies: protein kinases and their inhibitors in myocardial disease.Systems analysis reveals down-regulation of a network of pro-survival miRNAs drives the apoptotic response in dilated cardiomyopathy.Mitogen-activated protein kinases in heart development and diseases DUSP8 Regulates Cardiac Ventricular Remodeling by Altering ERK1/2 Signaling.Understanding the role of transforming growth factor-beta signalling in the heart: overview of studies using genetic mouse models.Stretch-induced regulation of angiotensinogen gene expression in cardiac myocytes and fibroblasts: opposing roles of JNK1/2 and p38alpha MAP kinases MAPK signalling in cardiovascular health and disease: molecular mechanisms and therapeutic targets.Parsing good versus bad signaling pathways in the heart: role of calcineurin-nuclear factor of activated T-cells.Cdc42 is an antihypertrophic molecular switch in the mouse heart.Therapeutic regulation of cardiac fibroblast function: targeting stress-activated protein kinase pathways.Role of the Wnt-Frizzled system in cardiac pathophysiology: a rapidly developing, poorly understood area with enormous potential.Heterodimerization of β2 adrenergic receptor and somatostatin receptor 5: Implications in modulation of signaling pathway.Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells.Systems biological approaches to the cardiac signaling network.Dual-specificity phosphatase 14 protects the heart from aortic banding-induced cardiac hypertrophy and dysfunction through inactivation of TAK1-P38MAPK/-JNK1/2 signaling pathway.

P2860

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P2860

c-Jun N-terminal kinases (JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT signaling.

http://www.wikidata.org/entity/Q39927730

description

2003 nî lūn-bûn

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

@zh-tw

2003年论文

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2003年论文

@zh

2003年论文

@zh-cn

name

c-Jun N-terminal kinases (JNK) ...... th calcineurin-NFAT signaling.

@en

c-Jun N-terminal kinases

@nl

type

label

c-Jun N-terminal kinases (JNK) ...... th calcineurin-NFAT signaling.

@en

c-Jun N-terminal kinases

@nl

prefLabel

c-Jun N-terminal kinases (JNK) ...... th calcineurin-NFAT signaling.

@en

c-Jun N-terminal kinases

@nl

P1433

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P932

Q39927730-267FE65B-0832-4D89-921B-7E72AF714BE3

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P1433

The EMBO Journal

P1476

c-Jun N-terminal kinases (JNK) ...... th calcineurin-NFAT signaling.

@en

P2093

Benjamin J Wilkins

http://www.w3.org/2001/XMLSchema#string

Chia-Yi Kuan

http://www.w3.org/2001/XMLSchema#string

Orlando F Bueno

http://www.w3.org/2001/XMLSchema#string

Qiangrong Liang

http://www.w3.org/2001/XMLSchema#string

Ying Xia

http://www.w3.org/2001/XMLSchema#string

P2860

JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway

Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth

Selective interaction of JNK protein kinase isoforms with transcription factors

Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7

Activated MEK5 induces serial assembly of sarcomeres and eccentric cardiac hypertrophy.

Phosphorylation of NFATc4 by p38 mitogen-activated protein kinases

The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase

The transcription factor GATA4 is activated by extracellular signal-regulated kinase 1- and 2-mediated phosphorylation of serine 105 in cardiomyocytes

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT

P304

5079-5089

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P31

scholarly article

P356

10.1093/EMBOJ/CDG474

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P407

P433

19

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P478

22

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P50

Jeffery D. Molkentin

P577

2003-10-01T00:00:00Z

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P5875

9074243

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P698

14517246

http://www.w3.org/2001/XMLSchema#string

P932

204458

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