Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter.
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From dynamic expression patterns to boundary formation in the presomitic mesodermPseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2Metal-dependent protein phosphatase 1A functions as an extracellular signal-regulated kinase phosphataseThe regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs)Negative feedback regulation of the ERK1/2 MAPK pathwayOverlapping functions of Pea3 ETS transcription factors in FGF signaling during zebrafish developmentTLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in miceSimultaneous visualization of both signaling cascade activity and end-point gene expression in single cellsp-MAPK1/3 and DUSP6 regulate epididymal cell proliferation and survival in a region-specific manner in mice.Charting Brachyury-mediated developmental pathways during early mouse embryogenesis.FGF signaling controls caudal hindbrain specification through Ras-ERK1/2 pathway.FGF21 resistance is not mediated by downregulation of beta-klotho expression in white adipose tissueDual specificity phosphatase 6 (DUSP6) is an ETS-regulated negative feedback mediator of oncogenic ERK signaling in lung cancer cells.Integration of signals along orthogonal axes of the vertebrate neural tube controls progenitor competence and increases cell diversityFOXO1-dependent up-regulation of MAP kinase phosphatase 3 (MKP-3) mediates glucocorticoid-induced hepatic lipid accumulation in miceDifferential up-regulation of MAP kinase phosphatases MKP3/DUSP6 and DUSP5 by Ets2 and c-Jun converge in the control of the growth arrest versus proliferation response of MCF-7 breast cancer cells to phorbol ester.Neurotoxic mechanisms of DNA damage: focus on transcriptional inhibition.Infrequent methylation of the DUSP6 phosphatase in endometrial cancer.Keratinocyte growth factor induces gene expression signature associated with suppression of malignant phenotype of cutaneous squamous carcinoma cells.Dual-specificity MAP kinase phosphatases (MKPs): shaping the outcome of MAP kinase signalling.The Fibroblast Growth Factor signaling pathwayAnalysis of FGF-dependent and FGF-independent pathways in otic placode inductionTSH signaling overcomes B-RafV600E-induced senescence in papillary thyroid carcinogenesis through regulation of DUSP6.Constitutively active Ras negatively regulates Erk MAP kinase through induction of MAP kinase phosphatase 3 (MKP3) in NIH3T3 cellsDual Specificity Phosphatase 5, a Specific Negative Regulator of ERK Signaling, Is Induced by Serum Response Factor and Elk-1 Transcription FactorEGFR inhibition evokes innate drug resistance in lung cancer cells by preventing Akt activity and thus inactivating Ets-1 functionSignalling by protein phosphatases and drug development: a systems-centred view.Research Resource: A Reference Transcriptome for Constitutive Androstane Receptor and Pregnane X Receptor Xenobiotic SignalingDUSPs, to MAP kinases and beyond.Endocytosis separates EGF receptors from endogenous fluorescently labeled HRas and diminishes receptor signaling to MAP kinases in endosomesA novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development.Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response.Cordycepin promotes apoptosis by modulating the ERK-JNK signaling pathway via DUSP5 in renal cancer cellsDown-regulation of DUSP6 expression in lung cancer: its mechanism and potential role in carcinogenesisETS2 mediated tumor suppressive function and MET oncogene inhibition in human non-small cell lung cancer.Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling.ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis.Association of Topoisomerase II (TOP2A) and Dual-Specificity Phosphatase 6 (DUSP6) Single Nucleotide Polymorphisms with Radiation Treatment Response and Prognosis of Lung Cancer in Han Chinese.The dual-specificity MAP kinase phosphatases: critical roles in development and cancer.Mitogen-Activated Protein (MAP) Kinase Scaffolding Proteins: A Recount.
P2860
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P2860
Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Negative-feedback regulation o ...... the DUSP6/MKP-3 gene promoter.
@en
type
label
Negative-feedback regulation o ...... the DUSP6/MKP-3 gene promoter.
@en
prefLabel
Negative-feedback regulation o ...... the DUSP6/MKP-3 gene promoter.
@en
P2093
P2860
P50
P356
P1433
P1476
Negative-feedback regulation o ...... the DUSP6/MKP-3 gene promoter.
@en
P2093
David M Owens
Laurent Delavaine
Maria Ekerot
Michael P Mitchell
Robin J Dickinson
P2860
P304
P356
10.1042/BJ20071512
P407
P577
2008-06-01T00:00:00Z