Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter. - Test2 - elhamkhani - TriplyDB

Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter.

Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter.

http://www.wikidata.org/entity/Q40005750

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From dynamic expression patterns to boundary formation in the presomitic mesoderm Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2 Metal-dependent protein phosphatase 1A functions as an extracellular signal-regulated kinase phosphatase The regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs)Negative feedback regulation of the ERK1/2 MAPK pathway Overlapping functions of Pea3 ETS transcription factors in FGF signaling during zebrafish development TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice Simultaneous visualization of both signaling cascade activity and end-point gene expression in single cells p-MAPK1/3 and DUSP6 regulate epididymal cell proliferation and survival in a region-specific manner in mice.Charting Brachyury-mediated developmental pathways during early mouse embryogenesis.FGF signaling controls caudal hindbrain specification through Ras-ERK1/2 pathway.FGF21 resistance is not mediated by downregulation of beta-klotho expression in white adipose tissue Dual specificity phosphatase 6 (DUSP6) is an ETS-regulated negative feedback mediator of oncogenic ERK signaling in lung cancer cells.Integration of signals along orthogonal axes of the vertebrate neural tube controls progenitor competence and increases cell diversity FOXO1-dependent up-regulation of MAP kinase phosphatase 3 (MKP-3) mediates glucocorticoid-induced hepatic lipid accumulation in mice Differential up-regulation of MAP kinase phosphatases MKP3/DUSP6 and DUSP5 by Ets2 and c-Jun converge in the control of the growth arrest versus proliferation response of MCF-7 breast cancer cells to phorbol ester.Neurotoxic mechanisms of DNA damage: focus on transcriptional inhibition.Infrequent methylation of the DUSP6 phosphatase in endometrial cancer.Keratinocyte growth factor induces gene expression signature associated with suppression of malignant phenotype of cutaneous squamous carcinoma cells.Dual-specificity MAP kinase phosphatases (MKPs): shaping the outcome of MAP kinase signalling.The Fibroblast Growth Factor signaling pathway Analysis of FGF-dependent and FGF-independent pathways in otic placode induction TSH signaling overcomes B-RafV600E-induced senescence in papillary thyroid carcinogenesis through regulation of DUSP6.Constitutively active Ras negatively regulates Erk MAP kinase through induction of MAP kinase phosphatase 3 (MKP3) in NIH3T3 cells Dual Specificity Phosphatase 5, a Specific Negative Regulator of ERK Signaling, Is Induced by Serum Response Factor and Elk-1 Transcription Factor EGFR inhibition evokes innate drug resistance in lung cancer cells by preventing Akt activity and thus inactivating Ets-1 function Signalling by protein phosphatases and drug development: a systems-centred view.Research Resource: A Reference Transcriptome for Constitutive Androstane Receptor and Pregnane X Receptor Xenobiotic Signaling DUSPs, to MAP kinases and beyond.Endocytosis separates EGF receptors from endogenous fluorescently labeled HRas and diminishes receptor signaling to MAP kinases in endosomes A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development.Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response.Cordycepin promotes apoptosis by modulating the ERK-JNK signaling pathway via DUSP5 in renal cancer cells Down-regulation of DUSP6 expression in lung cancer: its mechanism and potential role in carcinogenesis ETS2 mediated tumor suppressive function and MET oncogene inhibition in human non-small cell lung cancer.Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling.ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis.Association of Topoisomerase II (TOP2A) and Dual-Specificity Phosphatase 6 (DUSP6) Single Nucleotide Polymorphisms with Radiation Treatment Response and Prognosis of Lung Cancer in Han Chinese.The dual-specificity MAP kinase phosphatases: critical roles in development and cancer.Mitogen-Activated Protein (MAP) Kinase Scaffolding Proteins: A Recount.

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P2860

Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter.

http://www.wikidata.org/entity/Q40005750

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

Negative-feedback regulation o ...... the DUSP6/MKP-3 gene promoter.

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type

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Negative-feedback regulation o ...... the DUSP6/MKP-3 gene promoter.

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Negative-feedback regulation o ...... the DUSP6/MKP-3 gene promoter.

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Negative-feedback regulation o ...... the DUSP6/MKP-3 gene promoter.

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David M Owens

http://www.w3.org/2001/XMLSchema#string

Laurent Delavaine

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Maria Ekerot

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Michael P Mitchell

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Robin J Dickinson

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P2860

Isolation of the human genes encoding the pyst1 and Pyst2 phosphatases: characterisation of Pyst2 as a cytosolic dual-specificity MAP kinase phosphatase and its catalytic activation by both MAP and SAP kinases

Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase

Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways

Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors

The UCSC Genome Browser Database

Both nuclear-cytoplasmic shuttling of the dual specificity phosphatase MKP-3 and its ability to anchor MAP kinase in the cytoplasm are mediated by a conserved nuclear export signal

A role for MKP3 in axial patterning of the zebrafish embryo

Specificity and mechanism of action of some commonly used protein kinase inhibitors

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

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10.1042/BJ20071512

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2

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412

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Kate Gillian Storey

Marios P. Stavridis

Stephen M. Keyse

Christopher J Staples

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2008-06-01T00:00:00Z

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18321244

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2474557

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