Enhanced efficacy of combined HDAC and PARP targeting in glioblastoma.
about
Advances in epigenetic glioblastoma therapy.BRCA1-regulated RRM2 expression protects glioblastoma cells from endogenous replication stress and promotes tumorigenicity.Silencing of histone deacetylase 2 suppresses malignancy for proliferation, migration, and invasion of glioblastoma cells and enhances temozolomide sensitivity.Inhibition of histone deacetylases sensitizes glioblastoma cells to lomustine.Augmented antitumor activity by olaparib plus AZD1775 in gastric cancer through disrupting DNA damage repair pathways and DNA damage checkpoint.The p53 Pathway in GlioblastomaPARP inhibitor veliparib and HDAC inhibitor SAHA synergistically co-target the UHRF1/BRCA1 DNA damage repair complex in prostate cancer cellsInterplay of Histone Marks with Serine ADP-Ribosylation
P2860
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P2860
Enhanced efficacy of combined HDAC and PARP targeting in glioblastoma.
description
2016 nî lūn-bûn
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2016年の論文
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2016年学术文章
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2016年学术文章
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2016年学术文章
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2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
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2016年學術文章
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2016年學術文章
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name
Enhanced efficacy of combined HDAC and PARP targeting in glioblastoma.
@en
type
label
Enhanced efficacy of combined HDAC and PARP targeting in glioblastoma.
@en
prefLabel
Enhanced efficacy of combined HDAC and PARP targeting in glioblastoma.
@en
P2093
P2860
P1433
P1476
Enhanced efficacy of combined HDAC and PARP targeting in glioblastoma.
@en
P2093
Kamilla E Jensen
Madhavsai K Gajjar
Petra Hamerlik
Rikke D Rasmussen
P2860
P304
P356
10.1016/J.MOLONC.2015.12.014
P577
2016-01-08T00:00:00Z