Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
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Recurrent epimutations activate gene body promoters in primary glioblastomaIsocorydine inhibits cell proliferation in hepatocellular carcinoma cell lines by inducing G2/m cell cycle arrest and apoptosisAmino acid deprivation using enzymes as a targeted therapy for cancer and viral infectionsLarge-scale reconstruction of 3D structures of human chromosomes from chromosomal contact data.Recombinant methioninase effectively targets a Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model.Selective methioninase-induced trap of cancer cells in S/G2 phase visualized by FUCCI imaging confers chemosensitivity.S-adenosylmethionine stabilizes cystathionine beta-synthase and modulates redox capacity.Perspectives in cancer chemoprevention.Hierarchical and cybernetic nature of biologic systems and their relevance to homeostatic adaptation to low-level exposures to oxidative stress-inducing agents.Dietary methionine intake and risk of incident colorectal cancer: a meta-analysis of 8 prospective studies involving 431,029 participants.Enzymatic methyl esterification of erythrocyte membrane proteins is impaired in chronic renal failure. Evidence for high levels of the natural inhibitor S-adenosylhomocysteine.Uptake of 11C-methionine in breast cancer studied by PET. An association with the size of S-phase fraction.DNA methylation and polyamines in regulation of development of the fungus Mucor rouxii.Differential DNA methylation during the vegetative life cycle of Neurospora crassaDifferent levels of DNA methylation in yeast and mycelial forms of Candida albicansPurification, Characterization of L-Methioninase from Candida tropicalis, and Its Application as an Anticancer.Influence of L-methionine-deprived total parenteral nutrition with 5-fluorouracil on gastric cancer and host metabolismLoss of heterozygosity at the 5,10-methylenetetrahydrofolate reductase locus in human ovarian carcinomas.Serum folate, homocysteine and colorectal cancer risk in women: a nested case-control study.Antisense inhibition of methylenetetrahydrofolate reductase reduces survival of methionine-dependent tumour linesX chromosome reactivation in mouse embryonal carcinoma cellsAccuracy of methionine-PET in predicting the efficacy of heavy-particle therapy on primary adenoid cystic carcinomas of the head and neck.Prospective study of alcohol consumption and the risk of colorectal cancer before and after folic acid fortification in the United StatesTumor-specific cell-cycle decoy by Salmonella typhimurium A1-R combined with tumor-selective cell-cycle trap by methioninase overcome tumor intrinsic chemoresistance as visualized by FUCCI imaging.Mice heterozygous for germ-line mutations in methylthioadenosine phosphorylase (MTAP) die prematurely of T-cell lymphoma.Methionine-sensitive glycolysis in transformed cells.Imaging with non-FDG PET tracers: outlook for current clinical applications.The preclinical discovery of bacterial therapy for the treatment of metastatic cancer with unique advantages.Development of recombinant methioninase to target the general cancer-specific metabolic defect of methionine dependence: a 40-year odyssey.Is DNA methylation the new guardian of the genome?Methyl group deficiency in hepatocarcinogenesis.Patient-Derived Orthotopic Xenograft (PDOX) Models of Melanoma.Decrease in S-adenosylmethionine synthesis by 6-mercaptopurine and methylmercaptopurine ribonucleoside in Molt F4 human malignant lymphoblasts.Differential stimulation of S-adenosylmethionine decarboxylase by difluoromethylornithine in the rat colon and small intestine.L-methionase: a therapeutic enzyme to treat malignancies.Combination treatment with recombinant methioninase enables temozolomide to arrest a BRAF V600E melanoma in a patient-derived orthotopic xenograft (PDOX) mouse model.Targeting methionine with oral recombinant methioninase (o-rMETase) arrests a patient-derived orthotopic xenograft (PDOX) model of BRAF-V600E mutant melanoma: implications for chronic clinical cancer therapy and prevention.The wayward methyl group and the cascade to cancer.Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystine-glutamate antiporter xCT.Tumor-targeting Salmonella typhimurium A1-R combined with recombinant methioninase and cisplatinum eradicates an osteosarcoma cisplatinum-resistant lung metastasis in a patient-derived orthotopic xenograft (PDOX) mouse model: Decoy, trap and kill ch
P2860
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P2860
Altered methionine metabolism, DNA methylation and oncogene expression in carcinogenesis. A review and synthesis.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年学术文章
@wuu
1984年学术文章
@zh-cn
1984年学术文章
@zh-hans
1984年学术文章
@zh-my
1984年学术文章
@zh-sg
1984年學術文章
@yue
1984年學術文章
@zh
1984年學術文章
@zh-hant
name
Altered methionine metabolism, ...... nesis. A review and synthesis.
@en
type
label
Altered methionine metabolism, ...... nesis. A review and synthesis.
@en
prefLabel
Altered methionine metabolism, ...... nesis. A review and synthesis.
@en
P1476
Altered methionine metabolism, ...... nesis. A review and synthesis.
@en
P2093
R M Hoffman
P356
10.1016/0304-419X(84)90019-2
P577
1984-01-01T00:00:00Z