Calpain 2 and Src dependence distinguishes mesenchymal and amoeboid modes of tumour cell invasion: a link to integrin function.
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Talin contains a C-terminal calpain2 cleavage site important in focal adhesion dynamicsRac and Rho GTPases in cancer cell motility controlIntegrin activation by Fam38A uses a novel mechanism of R-Ras targeting to the endoplasmic reticulumAt the leading edge of three-dimensional cell migrationReduced expression of the ROCK inhibitor Rnd3 is associated with increased invasiveness and metastatic potential in mesenchymal tumor cellsTumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces.Initial steps of metastasis: cell invasion and endothelial transmigrationThree-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysisPlasticity of cell migration: a multiscale tuning modelMapping local matrix remodeling induced by a migrating tumor cell using three-dimensional multiple-particle tracking.Staged stromal extracellular 3D matrices differentially regulate breast cancer cell responses through PI3K and beta1-integrins.The tumor suppressor functions of p27(kip1) include control of the mesenchymal/amoeboid transition.Mechanosensitive Ca(2+) permeant cation channels in human prostate tumor cells.A peptide functionalized poly(ethylene glycol) (PEG) hydrogel for investigating the influence of biochemical and biophysical matrix properties on tumor cell migration.CD47 regulates collagen I-induced cyclooxygenase-2 expression and intestinal epithelial cell migration.High level of calpain1 promotes cancer cell invasion and migration in oral squamous cell carcinoma.Focal adhesion kinase, a downstream mediator of Raf-1 signaling, suppresses cellular adhesion, migration, and neuroendocrine markers in BON carcinoid cellsTumour cells expressing single VEGF isoforms display distinct growth, survival and migration characteristicsRho/ROCK signaling in motility and metastasis of gastric cancerLoss of the integrin-activating transmembrane protein Fam38A (Piezo1) promotes a switch to a reduced integrin-dependent mode of cell migration.Distinct roles for paxillin and Hic-5 in regulating breast cancer cell morphology, invasion, and metastasis.An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion.Calpains as potential anti-cancer targetsProtease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisitedScared stiff: Stabilizing the actin cytoskeleton to stop invading cancer cells in their tracks.Diverse roles for the paxillin family of proteins in cancer.Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion.Entry of Listeria monocytogenes in mammalian epithelial cells: an updated view.The calpains: modular designs and functional diversity.Inhibition of ROCK activity allows InlF-mediated invasion and increased virulence of Listeria monocytogenes.Snail levels control the migration mechanism of mesenchymal tumor cells.Mammalian Actin-binding Protein-1/Hip-55 Interacts with FHL2 and Negatively Regulates Cell InvasionNon-muscle myosin IIA differentially regulates intestinal epithelial cell restitution and matrix invasionAspirin Has Antitumor Effects via Expression of Calpain Gene in Cervical Cancer Cells.Stromagenesis during tumorigenesis: characterization of tumor-associated fibroblasts and stroma-derived 3D matrices.Serine protease HtrA1 associates with microtubules and inhibits cell migration.Distinct biophysical mechanisms of focal adhesion kinase mechanoactivation by different extracellular matrix proteins.Collagen-based cell migration models in vitro and in vivo.The molecular mechanisms of transition between mesenchymal and amoeboid invasiveness in tumor cells.Interstitial cell migration: integrin-dependent and alternative adhesion mechanisms.
P2860
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P2860
Calpain 2 and Src dependence distinguishes mesenchymal and amoeboid modes of tumour cell invasion: a link to integrin function.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Calpain 2 and Src dependence d ...... : a link to integrin function.
@en
type
label
Calpain 2 and Src dependence d ...... : a link to integrin function.
@en
prefLabel
Calpain 2 and Src dependence d ...... : a link to integrin function.
@en
P2093
P2860
P356
P1433
P1476
Calpain 2 and Src dependence d ...... n: a link to integrin function
@en
P2093
B W Ozanne
L A Scott Carragher
S M Walker
T K Sawyer
V G Brunton
P2860
P2888
P304
P356
10.1038/SJ.ONC.1209582
P407
P577
2006-05-01T00:00:00Z
P5875
P6179
1015744944