Structure-specific binding of the proto-oncogene protein DEK to DNA.
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The human DEK oncogene regulates DNA damage response signaling and repairThe SAF-box domain of chromatin protein DEKDissecting the Potential Interplay of DEK Functions in Inflammation and CancerSolution NMR structure of the N-terminal domain of the human DEK proteinThe DEK oncogene is a target of steroid hormone receptor signaling in breast cancerEffect of DNA supercoiling on the geometry of holliday junctionsCruciform structures are a common DNA feature important for regulating biological processes.High-affinity interaction of poly(ADP-ribose) and the human DEK oncoprotein depends upon chain length.Control of tumorigenesis and chemoresistance by the DEK oncogeneHigh expression of oncoprotein DEK predicts poor prognosis of small cell lung cancerThe human DEK proto-oncogene is a senescence inhibitor and an upregulated target of high-risk human papillomavirus E7The PML-associated protein DEK regulates the balance of H3.3 loading on chromatin and is important for telomere integrityDEK is a potential marker for aggressive phenotype and irinotecan-based therapy response in metastatic colorectal cancer.The human DEK oncogene stimulates β-catenin signaling, invasion and mammosphere formation in breast cancer.Apoptosis inhibition by the human DEK oncoprotein involves interference with p53 functions.The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation.The DEK Oncoprotein Is a Critical Component of the EKLF/KLF1 Enhancer in Erythroid Cells.DEK is required for homologous recombination repair of DNA breaks.Expression level of DEK in chronic lymphocytic leukemia is regulated by fludarabine and Nutlin-3 depending on p53 status.Stacking the DEK: from chromatin topology to cancer stem cells.DEK is a poly(ADP-ribose) acceptor in apoptosis and mediates resistance to genotoxic stressDEK proto-oncogene expression interferes with the normal epithelial differentiation program.The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF-1α-dependent and -independent manners.Progress in studies on the DEK protein and its involvement in cellular apoptosis.Chromatin redistribution of the DEK oncoprotein represses hTERT transcription in leukemiasConcise review: role of DEK in stem/progenitor cell biologyThe DEK oncoprotein and its emerging roles in gene regulation.The human oncoprotein and chromatin architectural factor DEK counteracts DNA replication stress.A role for intracellular and extracellular DEK in regulating hematopoiesis.p300/CBP-associated factor drives DEK into interchromatin granule clusters.Phosphorylation by protein kinase CK2 changes the DNA binding properties of the human chromatin protein DEKFunctional domains of the ubiquitous chromatin protein DEK.DEK-CAN molecular monitoring of myeloid malignancies could aid therapeutic stratification.A DEK domain-containing protein modulates chromatin structure and function in Arabidopsis.Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors.The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly(ADP-ribosyl)ation of p53 by PARP1.Negative regulation of the RelA/p65 transactivation function by the product of the DEK proto-oncogene.Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence.
P2860
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P2860
Structure-specific binding of the proto-oncogene protein DEK to DNA.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Structure-specific binding of the proto-oncogene protein DEK to DNA.
@en
type
label
Structure-specific binding of the proto-oncogene protein DEK to DNA.
@en
prefLabel
Structure-specific binding of the proto-oncogene protein DEK to DNA.
@en
P2093
P2860
P356
P1476
Structure-specific binding of the proto-oncogene protein DEK to DNA.
@en
P2093
Claudia Gruss
Martina Baack
Nicole Richter
Tanja Waldmann
P2860
P304
P356
10.1093/NAR/GKG864
P577
2003-12-01T00:00:00Z