Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor-induced apoptosis through positive feedback regulation of E2F1 apoptotic activity.
about
Histone deacetylase inhibitors: Potential in cancer therapyRegulation of Bim in Health and DiseaseAlcohol exposure alters cell cycle and apoptotic events during early neurulationIdentification of a candidate alternative promoter region of the human Bcl2L11 (Bim) geneA phase 2 study of intravenous panobinostat in patients with castration-resistant prostate cancer.Histone deacetylase inhibitors: a chemical genetics approach to understanding cellular functions.The clinical development of histone deacetylase inhibitors as targeted anticancer drugs.ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype.Histone deacetylase inhibitor (HDACI) mechanisms of action: emerging insights.Apoptosis signal-regulating kinase 1 and cyclin D1 compose a positive feedback loop contributing to tumor growth in gastric cancer.Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cellsEffects of SAHA on proliferation and apoptosis of hepatocellular carcinoma cells and hepatitis B virus replication.Vorinostat synergistically potentiates MK-0457 lethality in chronic myelogenous leukemia cells sensitive and resistant to imatinib mesylate.Stress signaling in cancer.HDAC inhibitors induce tumor-cell-selective pro-apoptotic transcriptional responses.Nitric oxide inactivates the retinoblastoma pathway in chronic inflammation.Hydroxamic acids (therapeutics and mechanism): chemistry, acyl nitroso, nitroxyl, reactive oxygen species, and cell signaling.Polycomb protein EZH2 regulates E2F1-dependent apoptosis through epigenetically modulating Bim expression.Transcriptional and post-translational regulation of Bim controls apoptosis in melatonin-treated human renal cancer Caki cells.E2F1 suppresses Wnt/β-catenin activity through transactivation of β-catenin interacting protein ICAT.Apoptosis signal-regulating kinase1 is inducible by protein kinase Cδ and contributes to phorbol ester-mediated G1 phase arrest through persistent JNK activation.Histone deacetylase inhibitors in the therapy of cancer: much to learn.The histone deacetylase inhibitor valproic acid alters growth properties of renal cell carcinoma in vitro and in vivo.
P2860
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P2860
Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor-induced apoptosis through positive feedback regulation of E2F1 apoptotic activity.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Apoptosis signal-regulating ki ...... on of E2F1 apoptotic activity.
@en
type
label
Apoptosis signal-regulating ki ...... on of E2F1 apoptotic activity.
@en
prefLabel
Apoptosis signal-regulating ki ...... on of E2F1 apoptotic activity.
@en
P2093
P2860
P356
P1476
Apoptosis signal-regulating ki ...... on of E2F1 apoptotic activity.
@en
P2093
Kevin K Yang
Krishina M Karuturi
P2860
P304
10508-10515
P356
10.1074/JBC.M512719200
P407
P577
2006-02-13T00:00:00Z