Fluorination Patterning: A Study of Structural Motifs That Impact Physicochemical Properties of Relevance to Drug Discovery.
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Weak Intermolecular Hydrogen Bonds with Fluorine: Detection and Implications for Enzymatic/Chemical Reactions, Chemical Properties, and Ligand/Protein Fluorine NMR Screening.Discovery of a Fluorinated Enigmol Analog with Enhanced in Vivo Pharmacokinetic and Anti-Tumor Properties.A practical and catalyst-free trifluoroethylation reaction of amines using trifluoroacetic acid.Catalytic, Diastereoselective 1,2-Difluorination of Alkenes.Stereochemistry and biological activity of chlorinated lipids: a study of danicalipin A and selected diastereomers.Effect of Partially Fluorinated N-Alkyl-Substituted Piperidine-2-carboxamides on Pharmacologically Relevant Properties.Structural and Conformational Aspects of Equatorial and Axial Trifluoromethyl, Difluoromethyl, and Monofluoromethyl Groups.Formation of α-SF5-Enolate Enables Preparation of 3-SF5-Quinolin-2-ones, 3-SF5-Quinolines, and 3-SF5-Pyridin-2-ones: Evaluation of their Physicochemical Properties.α-Trifluoromethylated tertiary homoallylic amines: diastereoselective synthesis and conversion into β-aminoesters, γ- and δ-aminoalcohols, azetidines and pyrrolidines.Fluorine-Substituted Pyrrolo[2,3- d]Pyrimidine Analogues with Tumor Targeting via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide Biosynthesis.
P2860
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P2860
Fluorination Patterning: A Study of Structural Motifs That Impact Physicochemical Properties of Relevance to Drug Discovery.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Fluorination Patterning: A Stu ...... f Relevance to Drug Discovery.
@en
type
label
Fluorination Patterning: A Stu ...... f Relevance to Drug Discovery.
@en
prefLabel
Fluorination Patterning: A Stu ...... f Relevance to Drug Discovery.
@en
P2093
P1476
Fluorination Patterning: A Stu ...... f Relevance to Drug Discovery.
@en
P2093
Bernd Kuhn
Björn Wagner
Daniel Zimmerli
Holger Fischer
Klaus Müller
Manfred Kansy
Nicole A Kratochwil
Quentin A Huchet
P304
P356
10.1021/ACS.JMEDCHEM.5B01455
P407
P577
2015-11-02T00:00:00Z