about
MORN1 has a conserved role in asexual and sexual development across the apicomplexaParasite Calcineurin Regulates Host Cell Recognition and Attachment by ApicomplexansA Toxoplasma MORN1 null mutant undergoes repeated divisions but is defective in basal assembly, apicoplast division and cytokinesisForward genetic screening identifies a small molecule that blocks Toxoplasma gondii growth by inhibiting both host- and parasite-encoded kinasesCompartmentalized Toxoplasma EB1 bundles spindle microtubules to secure accurate chromosome segregationA DOC2 protein identified by mutational profiling is essential for apicomplexan parasite exocytosisA MORN1-associated HAD phosphatase in the basal complex is essential for Toxoplasma gondii daughter buddingThe Toxoplasma gondii kinetochore is required for centrosome association with the centrocone (spindle pole)A family of intermediate filament-like proteins is sequentially assembled into the cytoskeleton of Toxoplasma gondiiTargeted proteomic dissection of Toxoplasma cytoskeleton sub-compartments using MORN1.The Toxoplasma gondii centrosome is the platform for internal daughter budding as revealed by a Nek1 kinase mutantFluorescent protein tagging in Toxoplasma gondii: identification of a novel inner membrane complex component conserved among Apicomplexa.Identification of a sporozoite-specific member of the Toxoplasma SAG superfamily via genetic complementation.Forward genetic analysis of the apicomplexan cell division cycle in Toxoplasma gondii.Chemogenomics and parasitology: small molecules and cell-based assays to study infectious processes.Differential regulation of effector- and central-memory responses to Toxoplasma gondii Infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells.Whole genome profiling of spontaneous and chemically induced mutations in Toxoplasma gondiiCytoskeleton assembly in Toxoplasma gondii cell division.Sarcocystis neurona merozoites express a family of immunogenic surface antigens that are orthologues of the Toxoplasma gondii surface antigens (SAGs) and SAG-related sequences.The Toxoplasma gondii calcium-dependent protein kinase 7 is involved in early steps of parasite division and is crucial for parasite survival.Simultaneous detection of bovine Theileria and Babesia species by reverse line blot hybridization.A MORN-repeat protein is a dynamic component of the Toxoplasma gondii cell division apparatus.High-throughput growth assay for Toxoplasma gondii using yellow fluorescent protein.Genetic basis for phenotypic differences between different Toxoplasma gondii type I strainsCD40 induces macrophage anti-Toxoplasma gondii activity by triggering autophagy-dependent fusion of pathogen-containing vacuoles and lysosomesApicomplexan cell cycle flexibility: centrosome controls the clutchCactin is essential for G1 progression in Toxoplasma gondii.Studying the cell biology of apicomplexan parasites using fluorescent proteins.A genetic screen to isolate Toxoplasma gondii host-cell egress mutantsLytic Cycle of Toxoplasma gondii: 15 Years Later.β-1,3-glucan, which can be targeted by drugs, forms a trabecular scaffold in the oocyst walls of Toxoplasma and EimeriaParasite stage-specific recognition of endogenous Toxoplasma gondii-derived CD8+ T cell epitopes.Evolution of apicomplexan secretory organelles.The FIKK kinase of Toxoplasma gondii is not essential for the parasite's lytic cycle.Gene transfer in the evolution of parasite nucleotide biosynthesis.The cell cycle and Toxoplasma gondii cell division: tightly knit or loosely stitched?Study of Theileria annulata population structure during bovine infection and following transmission to ticks.Generation of a mosaic pattern of diversity in the major merozoite-piroplasm surface antigen of Theileria annulata.Membrane skeletal association and post-translational allosteric regulation of Toxoplasma gondii GAPDH1.The conserved apicomplexan Aurora kinase TgArk3 is involved in endodyogeny, duplication rate and parasite virulence
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description
hulumtues
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researcher
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wetenschapper
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հետազոտող
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name
Marc-Jan Gubbels
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Marc-Jan Gubbels
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Marc-Jan Gubbels
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Marc-Jan Gubbels
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Marc-Jan Gubbels
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Marc-Jan Gubbels
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Marc-Jan Gubbels
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Marc-Jan Gubbels
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Marc-Jan Gubbels
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Marc-Jan Gubbels
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JM Gubbels
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Johannes M Gubbels
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Marc-Jan Gubbels
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Marc-Jan Gubbels
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Marc-Jan Gubbels
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Marc-Jan Gubbels
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Marc-Jan Gubbels
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P106
P108
P21
P31
P496
0000-0002-2769-8600