Effect of hypoxia on Ad5 infection, transgene expression and replication.
about
The hTERT promoter enhances the antitumor activity of an oncolytic adenovirus under a hypoxic microenvironmentHypoxia enhances the replication of oncolytic herpes simplex virusAdvances in preclinical investigation of prostate cancer gene therapy.Spores of Clostridium engineered for clinical efficacy and safety cause regression and cure of tumors in vivoImpact of tumor microenvironment on oncolytic viral therapyOncolytic Viruses for Cancer Therapy: Overcoming the Obstacles.Oncolytic virotherapy: molecular targets in tumor-selective replication and carrier cell-mediated delivery of oncolytic virusesArmoring CRAds with p21/Waf-1 shRNAs: the next generation of oncolytic adenoviruses.Clostridial spores for cancer therapy: targeting solid tumour microenvironmentRepeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivoActin-resistant DNAse I Expression From Oncolytic Adenovirus Enadenotucirev Enhances Its Intratumoral Spread and Reduces Tumor Growth.Gene therapy approaches to enhance bioreductive drug treatment.Adenoviral vector-based strategies for cancer therapy.Antiglioma oncolytic virotherapy: unattainable goal or a success story in the making?HIF-1α downregulation and apoptosis in hypoxic prostate tumor cells infected with oncolytic mammalian orthoreovirus.Oncolytic viruses: a new class of immunotherapy drugs.Talimogene Laherparepvec (T-VEC) and Other Oncolytic Viruses for the Treatment of Melanoma.Lister strain vaccinia virus with thymidine kinase gene deletion is a tractable platform for development of a new generation of oncolytic virus.Potent antitumor activity of Oct4 and hypoxia dual-regulated oncolytic adenovirus against bladder cancer.An armed, YB-1-dependent oncolytic adenovirus as a candidate for a combinatorial anti-glioma approach of virotherapy, suicide gene therapy and chemotherapeutic treatment.Low oxygen tension enhances hepatitis C virus replication.Vascular endothelial growth factor A promotes vaccinia virus entry into host cells via activation of the Akt pathway.Oncolytic viral therapy for pancreatic cancer.Treatment of pancreatic cancer with an oncolytic adenovirus expressing interleukin-12 in Syrian hamsters.Lister strain vaccinia virus, a potential therapeutic vector targeting hypoxic tumours.Downregulation of the coxsackie and adenovirus receptor in cancer cells by hypoxia depends on HIF-1alpha.Oncolytic Viral Therapy for Mesothelioma.Potent antitumor effect of tumor microenvironment-targeted oncolytic adenovirus against desmoplastic pancreatic cancer.Second-generation HIF-activated oncolytic adenoviruses with improved replication, oncolytic, and antitumor efficacyThe effect of hypoxia on the uptake, replication and lytic potential of group B adenovirus type 3 (Ad3) and type 11p (Ad11p).A hypoxia- and telomerase-responsive oncolytic adenovirus expressing secretable trimeric TRAIL triggers tumour-specific apoptosis and promotes viral dispersion in TRAIL-resistant glioblastoma.YB-1 dependent virotherapy in combination with temozolomide as a multimodal therapy approach to eradicate malignant glioma.Hepatocellular carcinoma-targeting oncolytic adenovirus overcomes hypoxic tumor microenvironment and effectively disperses through both central and peripheral tumor regions.
P2860
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P2860
Effect of hypoxia on Ad5 infection, transgene expression and replication.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Effect of hypoxia on Ad5 infection, transgene expression and replication.
@en
type
label
Effect of hypoxia on Ad5 infection, transgene expression and replication.
@en
prefLabel
Effect of hypoxia on Ad5 infection, transgene expression and replication.
@en
P2860
P356
P1433
P1476
Effect of hypoxia on Ad5 infection, transgene expression and replication.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.GT.3302448
P577
2005-06-01T00:00:00Z
P5875
P6179
1005301089