Natural mutations in IFITM3 modulate post-translational regulation and toggle antiviral specificity.
about
Zika virus induces massive cytoplasmic vacuolization and paraptosis-like death in infected cells.Accurate characterization of the IFITM locus using MiSeq and PacBio sequencing shows genetic variation in GalliformesRhesus macaque IFITM3 gene polymorphisms and SIV infection.IFITM3 Rs12252-C Variant Increases Potential Risk for Severe Influenza Virus Infection in Chinese Population.IFITM3 requires an amphipathic helix for antiviral activity.Human Genetic Determinants of Viral Diseases.Δ20 IFITM2 differentially restricts X4 and R5 HIV-1.SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans.Interference with the production of infectious viral particles and bimodal inhibition of replication are broadly conserved antiviral properties of IFITMs.More than meets the I: the diverse antiviral and cellular functions of interferon-induced transmembrane proteins.Association of IFITM3 rs12252 polymorphisms, BMI, diabetes, and hypercholesterolemia with mild flu in an Iranian population.Identification of residues controlling restriction versus enhancing activities of IFITM proteins on the entry of human coronaviruses.Lack of Truncated IFITM3 Transcripts in Cells Homozygous for the rs12252-C Variant That is Associated With Severe Influenza Infection.Inhibiting the Ins and Outs of HIV Replication: Cell-Intrinsic Antiretroviral Restrictions at the Plasma Membrane.The palmitoyltransferase ZDHHC20 enhances interferon-induced transmembrane protein 3 (IFITM3) palmitoylation and antiviral activity.Pilot screening study of targeted genetic polymorphisms for association with seasonal influenza hospital admission.The Inhibition of HIV-1 Entry Imposed by Interferon Inducible Transmembrane Proteins Is Independent of Co-Receptor UsagemTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3IFITM proteins inhibit HIV-1 protein synthesis
P2860
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P2860
Natural mutations in IFITM3 modulate post-translational regulation and toggle antiviral specificity.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Natural mutations in IFITM3 mo ...... toggle antiviral specificity.
@en
type
label
Natural mutations in IFITM3 mo ...... toggle antiviral specificity.
@en
prefLabel
Natural mutations in IFITM3 mo ...... toggle antiviral specificity.
@en
P2093
P2860
P356
P1433
P1476
Natural mutations in IFITM3 mo ...... toggle antiviral specificity.
@en
P2093
Anne Billet
Chen Liang
Françoise Porrot
Jacob S Yount
Nicolas Roy
Nicoletta Casartelli
P2860
P304
P356
10.15252/EMBR.201642771
P577
2016-09-06T00:00:00Z