Chronic myelocytic leukemia: clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage.
about
Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemiaRole of tyrosine-kinase inhibitors in myeloproliferative neoplasms: comparative lessons learnedMicroRNAs mediated regulation of MAPK signaling pathways in chronic myeloid leukemiaBladder Cancer Stem-Like Cells: Their Origin and Therapeutic PerspectivesIs lineage decision-making restricted during tumoral reprograming of haematopoietic stem cells?PIG-A mutations in paroxysmal nocturnal hemoglobinuria and in normal hematopoiesisFeverfew: weeding out the root of leukaemiaBCR/ABL-mediated downregulation of genes implicated in cell adhesion and motility leads to impaired migration toward CCR7 ligands CCL19 and CCL21 in primary BCR/ABL-positive cellsLSK derived LSK- cells have a high apoptotic rate related to survival regulation of hematopoietic and leukemic stem cellsBCR/ABL induces chromosomal instability after genotoxic stress and alters the cell death thresholdImatinib mesylate and nilotinib (AMN107) exhibit high-affinity interaction with ABCG2 on primitive hematopoietic stem cells.Pre-leukemic evolution of hematopoietic stem cells: the importance of early mutations in leukemogenesisThe E. Donnall Thomas lecture: normal and neoplastic stem cells.Induction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cellsChromosomal translocation in a human leukemic stem-cell line disrupts the T-cell antigen receptor delta-chain diversity region and results in a previously unreported fusion transcript.bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.Chronic myelogenous leukemia--recent advances in treatment and pathogenesis.Clinical and epidemiological features of acute lymphoblastic leukemia following a previous malignancy.Modeling Philadelphia chromosome positive leukemias.Persistence of transcriptionally silent BCR-ABL rearrangements in chronic myeloid leukemia patients in sustained complete cytogenetic remission.T cells and probably B cells arise from the malignant clone in chronic myelogenous leukemia.Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?The controversial role of the Hedgehog pathway in normal and malignant hematopoiesis.Right on target: eradicating leukemic stem cells.Clonal analysis of agnogenic myeloid metaplasia.Osteoblast ablation reduces normal long-term hematopoietic stem cell self-renewal but accelerates leukemia development.Treatment of chronic myelogenous leukemia by blocking cytokine alterations found in normal stem and progenitor cellsFurther phenotypic characterization of the primitive lineage- CD34+CD38-CD90+CD45RA- hematopoietic stem cell/progenitor cell sub-population isolated from cord blood, mobilized peripheral blood and patients with chronic myelogenous leukemia.Cytogenetic abnormalities in childhood acute lymphoblastic leukemia correlates with clinical features and treatment outcome.Considerations for targeting malignant stem cells in leukemia.Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias.Mechanisms controlling pathogenesis and survival of leukemic stem cells.Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemiaStem cells in prostate cancer initiation and progression.Age-related defects in B lymphopoiesis underlie the myeloid dominance of adult leukemiaMolecular evidence for the clonal origin of blast crisis in chronic myeloid leukaemia.Diverging fates of cells of origin in acute and chronic leukaemia.Different roles of TGF-β in the multi-lineage differentiation of stem cells.Studies on the clonal origin of multiple myeloma. Use of individually specific (idiotype) antibodies to trace the oncogenic event to its earliest point of expression in B-cell differentiation.
P2860
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P2860
Chronic myelocytic leukemia: clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage.
description
1977 nî lūn-bûn
@nan
1977年の論文
@ja
1977年学术文章
@wuu
1977年学术文章
@zh-cn
1977年学术文章
@zh-hans
1977年学术文章
@zh-my
1977年学术文章
@zh-sg
1977年學術文章
@yue
1977年學術文章
@zh
1977年學術文章
@zh-hant
name
Chronic myelocytic leukemia: c ...... telet and monocyte/macrophage.
@en
type
label
Chronic myelocytic leukemia: c ...... telet and monocyte/macrophage.
@en
prefLabel
Chronic myelocytic leukemia: c ...... telet and monocyte/macrophage.
@en
P2093
P1476
Chronic myelocytic leukemia: c ...... telet and monocyte/macrophage.
@en
P2093
P J Fialkow
R J Jacobson
T Papayannopoulou
P304
P356
10.1016/0002-9343(77)90124-3
P407
P577
1977-07-01T00:00:00Z