Smad-binding defective mutant of transforming growth factor beta type I receptor enhances tumorigenesis but suppresses metastasis of breast cancer cell lines.
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Breast cancer bone metastasis mediated by the Smad tumor suppressor pathwayTransient tumor-fibroblast interactions increase tumor cell malignancy by a TGF-Beta mediated mechanism in a mouse xenograft model of breast cancerEffects of supplemental vitamin D and calcium on normal colon tissue and circulating biomarkers of risk for colorectal neoplasmsSmad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesisA thrombospondin-1 antagonist of transforming growth factor-beta activation blocks cardiomyopathy in rats with diabetes and elevated angiotensin IISmad4-expression is decreased in breast cancer tissues: a retrospective study.Context-dependent function of the deubiquitinating enzyme USP9X in pancreatic ductal adenocarcinomaTgf-beta signaling pathway in lung adenocarcinoma invasion.MRC2 expression correlates with TGFβ1 and survival in hepatocellular carcinoma.Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression.Loss of N-Myc interactor promotes epithelial-mesenchymal transition by activation of TGF-β/SMAD signaling.LY2109761, a novel transforming growth factor beta receptor type I and type II dual inhibitor, as a therapeutic approach to suppressing pancreatic cancer metastasis.Chemotherapeutic Targeting of the Transforming Growth Factor-β Pathway in Breast Cancers.Vimentin is sufficient and required for wound repair and remodeling in alveolar epithelial cells.The complexities of TGF-β action during mammary and squamous cell carcinogenesis.Role of transforming growth factor-beta in cancer progression.The Dual Role of TGFβ in Human Cancer: From Tumor Suppression to Cancer MetastasisEctodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-beta/BMP signaling during tooth and palate development.Noncanonical TGF-β signaling during mammary tumorigenesis.TGFBR1*6A enhances the migration and invasion of MCF-7 breast cancer cells through RhoA activation.Co-expression of LASS2 and TGF-β1 predicts poor prognosis in hepatocellular carcinoma.The TGF-beta paradox in human cancer: an update.The type III transforming growth factor-beta receptor negatively regulates nuclear factor kappa B signaling through its interaction with beta-arrestin2.Multiple forms of BRMS1 are differentially expressed in the MCF10 isogenic breast cancer progression model.Growth factor signaling in metastasis: current understanding and future opportunities.The rejuvenated scenario of epithelial-mesenchymal transition (EMT) and cancer metastasis.Proteinase-activated receptor 2 promotes TGF-β-dependent cell motility in pancreatic cancer cells by sustaining expression of the TGF-β type I receptor ALK5.The TGF-β/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system.Smad signaling is required to maintain epigenetic silencing during breast cancer progression.Dual role of Ski in pancreatic cancer cells: tumor-promoting versus metastasis-suppressive function.TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch.PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production.Ki26894, a novel transforming growth factor-beta type I receptor kinase inhibitor, inhibits in vitro invasion and in vivo bone metastasis of a human breast cancer cell line.Cripto binds transforming growth factor beta (TGF-beta) and inhibits TGF-beta signaling.Release the ink4a/arf growth suppression by "u" and "me"?The atypical chemokine receptor CCX-CKR regulates metastasis of mammary carcinoma via an effect on EMT.KLF10 loss in the pancreas provokes activation of SDF-1 and induces distant metastases of pancreatic ductal adenocarcinoma in the KrasG12D p53flox/flox model.
P2860
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P2860
Smad-binding defective mutant of transforming growth factor beta type I receptor enhances tumorigenesis but suppresses metastasis of breast cancer cell lines.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Smad-binding defective mutant ...... s of breast cancer cell lines.
@en
type
label
Smad-binding defective mutant ...... s of breast cancer cell lines.
@en
prefLabel
Smad-binding defective mutant ...... s of breast cancer cell lines.
@en
P2093
P50
P1433
P1476
Smad-binding defective mutant ...... s of breast cancer cell lines.
@en
P2093
Deepa Nemani
Stacey DaCosta Byfield
W Tony Parks
P304
P356
10.1158/0008-5472.CAN-04-0030
P407
P577
2004-07-01T00:00:00Z