about
The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancerMiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastomaTherapeutic efficacy by targeting correction of Notch1-induced aberrants in uveal tumorsPathways contributing to development of spontaneous mammary tumors in BALB/c-Trp53+/- mice.Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient miceRestoration of p53 expression in human cancer cell lines upregulates the expression of Notch1: implications for cancer cell fate determination after genotoxic stressRegulation of Notch1 gene expression by p53 in epithelial cellsp53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating With the Notch Transcriptional Complex Via MAML1Repression of mammary stem/progenitor cells by p53 is mediated by Notch and separable from apoptotic activity.Mutant p53-Notch1 Signaling Axis Is Involved in Curcumin-Induced Apoptosis of Breast Cancer Cells.Notch tumor suppressor functionPre-TCR signaling inactivates Notch1 transcription by antagonizing E2A.Thymus and aging: morphological, radiological, and functional overview.Tumor cell vascular mimicry: Novel targeting opportunity in melanoma.TAp73 isoforms antagonize Notch signalling in SH-SY5Y neuroblastomas and in primary neurones.Notch1 promotes survival of E2A-deficient T cell lymphomas through pre-T cell receptor-dependent and -independent mechanisms.miR-34a is involved in CSE-induced apoptosis of human pulmonary microvascular endothelial cells by targeting Notch-1 receptor protein.NOTCH1 gene transcriptionActivated Notch1 interacts with p53 to inhibit its phosphorylation and transactivation.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
p53 regulates thymic Notch1 activation.
@en
type
label
p53 regulates thymic Notch1 activation.
@en
prefLabel
p53 regulates thymic Notch1 activation.
@en
P2860
P356
P1476
p53 regulates thymic Notch1 activation.
@en
P2093
Amy M Laws
Barbara A Osborne
P2860
P304
P356
10.1002/EJI.200324772
P407
P577
2004-03-01T00:00:00Z