The taxol supply crisis. New NCI policies for handling the large-scale production of novel natural product anticancer and anti-HIV agents.
about
Discovery and resupply of pharmacologically active plant-derived natural products: A reviewTaxol biosynthesis: taxane 13 alpha-hydroxylase is a cytochrome P450-dependent monooxygenaseInspirations, discoveries, and future perspectives in total synthesisCyclization of geranylgeranyl diphosphate to taxa-4(5),11(12)-diene is the committed step of taxol biosynthesis in Pacific yewModern natural products drug discovery and its relevance to biodiversity conservationDiscovery and development of antineoplastic agents from natural sources.Taxol biosynthesis and molecular geneticsTraditional treatment of human and animal salmonelloses in Southern Benin: Knowledge of farmers and traditherapists.Marine natural products: a new wave of drugs?Molecular cloning of a cytochrome P450 taxane 10 beta-hydroxylase cDNA from Taxus and functional expression in yeastMetabolic engineering of plant alkaloid biosynthesis.From nature to the laboratory and into the clinicDNA fragmentation and apoptosis induced by safranal in human prostate cancer cell line.Prospective randomised evaluation of traditional Chinese medicine combined with chemotherapy: a randomised phase II study of wild toad extract plus gemcitabine in patients with advanced pancreatic adenocarcinomas.Anticancer drugs from nature--natural products as a unique source of new microtubule-stabilizing agents.Paclitaxel: a review of adverse toxicities and novel delivery strategies.Genome sequencing and analysis of the paclitaxel-producing endophytic fungus Penicillium aurantiogriseum NRRL 62431.Current approaches toward production of secondary plant metabolites.Metabolic engineering of Nicotiana benthamiana for the increased production of taxadiene.Plant cytochrome P450s: nomenclature and involvement in natural product biosynthesis.Natural products for human health: an historical overview of the drug discovery approaches.Use of GC/MS to identify chemical constituents and cytotoxic activity of the leaves of Phoradendron mucronatum and Phoradendron microphyllum (Viscaceae).Antiproliferative activity of Solanum lycocarpum alkaloidic extract and their constituents, solamargine and solasonine, in tumor cell lines.Transcriptome Assembly and Systematic Identification of Novel Cytochrome P450s in Taxus chinensis.Abscisic acid plays critical role in ozone-induced taxol production of Taxus chinensis suspension cell cultures.CYP725A4 from yew catalyzes complex structural rearrangement of taxa-4(5),11(12)-diene into the cyclic ether 5(12)-oxa-3(11)-cyclotaxane.Computational identification of gene over-expression targets for metabolic engineering of taxadiene production.Elicitors Derived from Hazel (Corylus avellana L.) Cell Suspension Culture Enhance Growth and Paclitaxel Production of Epicoccum nigrum
P2860
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P2860
The taxol supply crisis. New NCI policies for handling the large-scale production of novel natural product anticancer and anti-HIV agents.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
The taxol supply crisis. New N ...... nticancer and anti-HIV agents.
@en
type
label
The taxol supply crisis. New N ...... nticancer and anti-HIV agents.
@en
prefLabel
The taxol supply crisis. New N ...... nticancer and anti-HIV agents.
@en
P2093
P356
P1476
The taxol supply crisis. New N ...... nticancer and anti-HIV agents.
@en
P2093
Schepartz SA
Suffness M
P304
P356
10.1021/NP50100A001
P577
1993-10-01T00:00:00Z