Mitochondrial dysfunction is involved in apoptosis induced by serum withdrawal and fatty acids in the beta-cell line INS-1.
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Carboxypeptidase E mediates palmitate-induced beta-cell ER stress and apoptosisGuards and culprits in the endoplasmic reticulum: glucolipotoxicity and β-cell failure in type II diabetesChaperones ameliorate beta cell dysfunction associated with human islet amyloid polypeptide overexpressionRole of ceramide in diabetes mellitus: evidence and mechanisms.Survival signaling by C-RAF: mitochondrial reactive oxygen species and Ca2+ are critical targetsLack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated beta-cell death.Group VIA phospholipase A2 mitigates palmitate-induced β-cell mitochondrial injury and apoptosisGlucolipotoxicity of the pancreatic beta cell.AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome.Involvement of dynamin-related protein 1 in free fatty acid-induced INS-1-derived cell apoptosisIslet beta cell failure in type 2 diabetesDiet-induced obesity exacerbates auditory degeneration via hypoxia, inflammation, and apoptosis signaling pathways in CD/1 miceApoptosis-inducing factor: structure, function, and redox regulation.Stearoyl-coenzyme A desaturase 1 inhibition and the metabolic syndrome: considerations for future drug discoveryEffect of Australian propolis from stingless bees (Tetragonula carbonaria) on pre-contracted human and porcine isolated arteries.Characterisation of age-dependent beta cell dynamics in the male db/db mice.Changes in mitochondrial carriers exhibit stress-specific signatures in INS-1Eβ-cells exposed to glucose versus fatty acids.Prooxidant properties of p66shc are mediated by mitochondria in human cellsProteasome dysfunction mediates high glucose-induced apoptosis in rodent beta cells and human isletsSphingolipids in cardiovascular diseases and metabolic disordersp38 MAPK Is Activated but Does Not Play a Key Role during Apoptosis Induction by Saturated Fatty Acid in Human Pancreatic β-Cells.A simple matter of life and death-the trials of postnatal Beta-cell mass regulationA role for aberrant protein palmitoylation in FFA-induced ER stress and β-cell deathDeath protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis.Fenugreek lactone attenuates palmitate-induced apoptosis and dysfunction in pancreatic β-cellsBacterial-excreted small volatile molecule 2-aminoacetophenone induces oxidative stress and apoptosis in murine skeletal muscle.NADPH oxidase inhibition prevents beta cell dysfunction induced by prolonged elevation of oleate in rodents.Glucolipotoxicity: fuel excess and beta-cell dysfunction.Exendin-4 Promotes Survival of Mouse Pancreatic β-Cell Line in Lipotoxic Conditions, through the Extracellular Signal-Related Kinase 1/2 PathwayBeta-cell failure as a complication of diabetes.Proteins altered by elevated levels of palmitate or glucose implicated in impaired glucose-stimulated insulin secretion.Anti-oxidative effects of Rooibos tea (Aspalathus linearis) on immobilization-induced oxidative stress in rat brainNanospaces between endoplasmic reticulum and mitochondria as control centres of pancreatic β-cell metabolism and survival.Serotonin- and Dopamine-Related Gene Expression in db/db Mice Islets and in MIN6 β-Cells Treated with Palmitate and Oleate.Curcumin attenuates palmitate-induced apoptosis in MIN6 pancreatic β-cells through PI3K/Akt/FoxO1 and mitochondrial survival pathways.Bcl-2 maintains the mitochondrial membrane potential, but fails to affect production of reactive oxygen species and endoplasmic reticulum stress, in sodium palmitate-induced β-cell death.Novel insights into pancreatic β-cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells.Macrophage migration inhibitory factor (MIF) enhances palmitic acid- and glucose-induced murine beta cell dysfunction and destruction in vitro.Preconditioning and acute effects of flavonoids in protecting cardiomyocytes from oxidative cell death.Lipotoxicity-mediated cell dysfunction and death involve lysosomal membrane permeabilization and cathepsin L activity.
P2860
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P2860
Mitochondrial dysfunction is involved in apoptosis induced by serum withdrawal and fatty acids in the beta-cell line INS-1.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Mitochondrial dysfunction is i ...... s in the beta-cell line INS-1.
@en
type
label
Mitochondrial dysfunction is i ...... s in the beta-cell line INS-1.
@en
prefLabel
Mitochondrial dysfunction is i ...... s in the beta-cell line INS-1.
@en
P2093
P50
P356
P1433
P1476
Mitochondrial dysfunction is i ...... ds in the beta-cell line INS-1
@en
P2093
Bernat Soria
Isabel Maestre
Juan Antonio Reig
Marc Prentki
Soledad Calvo
P304
P356
10.1210/EN.2001-211282
P407
P577
2003-01-01T00:00:00Z