Cell surface tumor endothelium marker 8 cytoplasmic tail-independent anthrax toxin binding, proteolytic processing, oligomer formation, and internalization
about
Anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeletonEST-based genome-wide gene inactivation identifies ARAP3 as a host protein affecting cellular susceptibility to anthrax toxinReceptor-specific requirements for anthrax toxin delivery into cellsBinary bacterial toxins: biochemistry, biology, and applications of common Clostridium and Bacillus proteinsAnthrax toxin triggers endocytosis of its receptor via a lipid raft-mediated clathrin-dependent processMembrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathwayHuman capillary morphogenesis protein 2 functions as an anthrax toxin receptorReceptor palmitoylation and ubiquitination regulate anthrax toxin endocytosisRoles of Anthrax Toxin Receptor 2 in Anthrax Toxin Membrane Insertion and Pore FormationAnthrax lethal and edema toxins in anthrax pathogenesisBacillus anthracis edema factor substrate specificity: evidence for new modes of actionLRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxinThe Protective Antigen Component of Anthrax Toxin Forms Functional Octameric ComplexesCandida albicans Ssa1/2p is the cell envelope binding protein for human salivary histatin 5Cathepsin B-mediated autophagy flux facilitates the anthrax toxin receptor 2-mediated delivery of anthrax lethal factor into the cytoplasmDetection of anthrax toxin by an ultrasensitive immunoassay using europium nanoparticlesInduction of neutralizing antibody responses to anthrax protective antigen by using influenza virus vectors: implications for disparate immune system priming pathwaysA high-affinity monoclonal antibody to anthrax protective antigen passively protects rabbits before and after aerosolized Bacillus anthracis spore challengeCapillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo.Enhancement of anthrax lethal toxin cytotoxicity: a subset of monoclonal antibodies against protective antigen increases lethal toxin-mediated killing of murine macrophagesSelection of a macaque Fab with framework regions like those in humans, high affinity, and ability to neutralize the protective antigen (PA) of Bacillus anthracis by binding to the segment of PA between residues 686 and 694.Cationic polyamines inhibit anthrax lethal factor proteaseQuantitative high-throughput screening identifies inhibitors of anthrax-induced cell deathCharacterization of a Chinese hamster ovary cell mutant having a mutation in elongation factor-2.Endocytosis of the anthrax toxin is mediated by clathrin, actin and unconventional adaptorsMapping dominant-negative mutations of anthrax protective antigen by scanning mutagenesis.Anthrax toxin receptor drives protective antigen oligomerization and stabilizes the heptameric and octameric oligomer by a similar mechanism.Maturation modulates caspase-1-independent responses of dendritic cells to Anthrax lethal toxinKey tissue targets responsible for anthrax-toxin-induced lethality.Oral spore vaccine based on live attenuated nontoxinogenic Bacillus anthracis expressing recombinant mutant protective antigen.Chimeric influenza virus hemagglutinin proteins containing large domains of the Bacillus anthracis protective antigen: protein characterization, incorporation into infectious influenza viruses, and antigenicity.Endosomal recycling regulates Anthrax Toxin Receptor 1/Tumor Endothelial Marker 8-dependent cell spreading.Efficient targeting of head and neck squamous cell carcinoma by systemic administration of a dual uPA and MMP-activated engineered anthrax toxin.Tumor endothelium marker-8 based decoys exhibit superiority over capillary morphogenesis protein-2 based decoys as anthrax toxin inhibitors.Protection from anthrax toxin-mediated killing of macrophages by the combined effects of furin inhibitors and chloroquine.Anthrax toxin receptor 1/tumor endothelial marker 8: mutation of conserved inserted domain residues overrides cytosolic control of protective antigen bindingPassive protection against anthrax by using a high-affinity antitoxin antibody fragment lacking an Fc regionVaccination of rhesus macaques with the anthrax vaccine adsorbed vaccine produces a serum antibody response that effectively neutralizes receptor-bound protective antigen in vitro.A FRET-based high throughput screening assay to identify inhibitors of anthrax protective antigen binding to capillary morphogenesis gene 2 proteinBroad expression analysis of human ANTXR1/TEM8 transcripts reveals differential expression and novel splizce variants
P2860
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P2860
Cell surface tumor endothelium marker 8 cytoplasmic tail-independent anthrax toxin binding, proteolytic processing, oligomer formation, and internalization
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Cell surface tumor endothelium ...... formation, and internalization
@en
type
label
Cell surface tumor endothelium ...... formation, and internalization
@en
prefLabel
Cell surface tumor endothelium ...... formation, and internalization
@en
P2860
P243
P356
P1476
Cell surface tumor endothelium ...... formation, and internalization
@en
P243
P2860
P304
P356
10.1074/JBC.M210321200
P4011
56ae3db9d1fcc21c65d560b8e69ea182706903e1
P407
P5530
P577
2002-12-04T00:00:00Z
P5875
P6179
1041940882