about
Role of CLASP2 in microtubule stabilization and the regulation of persistent motilityA targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumorsPaneth cells in intestinal homeostasis and tissue injuryCancer stemness in Apc- vs. Apc/KRAS-driven intestinal tumorigenesisIdentification of quiescent, stem-like cells in the distal female reproductive tractFamilial endometrial cancer in female carriers of MSH6 germline mutationsThe APC gene in colorectal cancerInvolvement of MBD4 inactivation in mismatch repair-deficient tumorigenesisDynamic expression and nuclear accumulation of beta-catenin during the development of hair follicle-derived structuresAneuploidy arises at early stages of Apc-driven intestinal tumorigenesis and pinpoints conserved chromosomal loci of allelic imbalance between mouse and humanApc1638N: a mouse model for familial adenomatous polyposis-associated desmoid tumors and cutaneous cystsA novel frameshift mutation [FSC 47 (+A)] causing beta-thalassemia in a Surinam patient.Leiden Open Variation Database of the MUTYH gene.Targeted deletion of the C-terminus of the mouse adenomatous polyposis coli tumor suppressor results in neurologic phenotypes related to schizophrenia.Chromosomal instability in MYH- and APC-mutant adenomatous polyps.Stem cells and metastatic cancer: fatal attraction?Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursorsA targeted constitutive mutation in the APC tumor suppressor gene underlies mammary but not intestinal tumorigenesisMolecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene.The CHEK2 1100delC mutation identifies families with a hereditary breast and colorectal cancer phenotype.Familial adenomatous polyposis-associated desmoids display significantly more genetic changes than sporadic desmoids.Cancer biology. A matter of dosage.Proximal fluid proteome profiling of mouse colon tumors reveals biomarkers for early diagnosis of human colorectal cancer.Generation and characterization of an inducible transgenic model for studying mouse esophageal biology.Somatic acquisition and signaling of TGFBR1*6A in cancer.Wnt signaling regulates the lineage differentiation potential of mouse embryonic stem cells through Tcf3 down-regulation.Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis.Cross-species comparison of human and mouse intestinal polyps reveals conserved mechanisms in adenomatous polyposis coli (APC)-driven tumorigenesis.A randomized placebo-controlled prevention trial of aspirin and/or resistant starch in young people with familial adenomatous polyposis.Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trialCA repeat polymorphism within the MCC (mutated in colorectal cancer) geneAPC dosage effects in tumorigenesis and stem cell differentiation.SET-CAN, the product of the t(9;9) in acute undifferentiated leukemia, causes expansion of early hematopoietic progenitors and hyperproliferation of stomach mucosa in transgenic mice.Use of aspirin postdiagnosis improves survival for colon cancer patientsCD24 Is Not Required for Tumor Initiation and Growth in Murine Breast and Prostate Cancer Models.Junk DNA and the long non-coding RNA twist in cancer genetics.Phenotypic and genotypic heterogeneity in the Lynch syndrome: diagnostic, surveillance and management implications.Expression and genomic profiling of colorectal cancer.cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo.Wnt/beta-catenin signaling in cancer stemness and malignant behavior.
P50
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P50
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hulumtues
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հետազոտող
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Riccardo Fodde
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Riccardo Fodde
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Riccardo Fodde
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Riccardo Fodde
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Riccardo Fodde
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Riccardo Fodde
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Riccardo Fodde
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Riccardo Fodde
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Riccardo Fodde
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Riccardo Fodde
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Riccardo Fodde
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Riccardo Fodde
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P106
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7007028278
P21
P31
P496
0000-0001-9839-4324