Amylin receptor phenotypes derived from human calcitonin receptor/RAMP coexpression exhibit pharmacological differences dependent on receptor isoform and host cell environment.
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The inhibitory effect of salmon calcitonin on tri-iodothyronine induction of early hypertrophy in articular cartilageIncreased bone mass is an unexpected phenotype associated with deletion of the calcitonin geneAmyloid β (Aβ) peptide directly activates amylin-3 receptor subtype by triggering multiple intracellular signaling pathwaysThe Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsRole of calcitonin gene-related peptide in bone repair after cyclic fatigue loading.Amylin activates distributed CNS nuclei to control energy balance.Bacterial expression and purification of a heterodimeric adrenomedullin receptor extracellular domain complex using DsbC-assisted disulfide shuffling.Preparation and characterization of PEGylated amylin.Distinct internalization pathways of human amylin monomers and its cytotoxic oligomers in pancreatic cellsComparison of the expression of calcitonin receptor-like receptor (CRLR) and receptor activity modifying proteins (RAMPs) with CGRP and adrenomedullin binding in cell lines.Pharmacological characterization of rat amylin receptors: implications for the identification of amylin receptor subtypes.Class II G protein-coupled receptors and their ligands in neuronal function and protectionReceptor activity-modifying protein-dependent impairment of calcitonin receptor splice variant Δ(1-47)hCT((a)) function.Calcitonin and Amylin Receptor Peptide Interaction Mechanisms: INSIGHTS INTO PEPTIDE-BINDING MODES AND ALLOSTERIC MODULATION OF THE CALCITONIN RECEPTOR BY RECEPTOR ACTIVITY-MODIFYING PROTEINS.Endogenous VMH amylin signaling is required for full leptin signaling and protection from diet-induced obesity.An allosteric role for receptor activity-modifying proteins in defining GPCR pharmacology.Amylin structure-function relationships and receptor pharmacology: implications for amylin mimetic drug development.Fine-tuning of GPCR activity by receptor-interacting proteinsModulation of firing and synaptic transmission of serotonergic neurons by intrinsic G protein-coupled receptors and ion channels.Inhibitory effect of BIBN4096BS, CGRP(8-37), a CGRP antibody and an RNA-Spiegelmer on CGRP induced vasodilatation in the perfused and non-perfused rat middle cerebral artery.Receptor Activity-Modifying Proteins (RAMPs): New Insights and Roles.Targeting orphan G protein-coupled receptors for the treatment of diabetes and its complications: C-peptide and GPR146.Amylin Acts in the Lateral Dorsal Tegmental Nucleus to Regulate Energy Balance Through Gamma-Aminobutyric Acid Signaling.Receptor activity modifying proteins (RAMPs) interact with the VPAC2 receptor and CRF1 receptors and modulate their function.Type II Turn of Receptor-bound Salmon Calcitonin Revealed by X-ray Crystallography.CL/RAMP2 and CL/RAMP3 produce pharmacologically distinct adrenomedullin receptors: a comparison of effects of adrenomedullin22-52, CGRP8-37 and BIBN4096BS.Oral salmon calcitonin attenuates hyperglycaemia and preserves pancreatic beta-cell area and function in Zucker diabetic fatty rats.Selective CGRP and adrenomedullin peptide binding by tethered RAMP-calcitonin receptor-like receptor extracellular domain fusion proteins.Update on the pharmacology of calcitonin/CGRP family of peptides: IUPHAR Review 25.The Molecular Physiopathogenesis of Islet Amyloidosis.N-Glycosylation of Asparagine 130 in the Extracellular Domain of the Human Calcitonin Receptor Significantly Increases Peptide Hormone Affinity.RAMP2 Influences Glucagon Receptor Pharmacology via Trafficking and Signaling.Amylin in Alzheimer's disease: Pathological peptide or potential treatment?
P2860
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P2860
Amylin receptor phenotypes derived from human calcitonin receptor/RAMP coexpression exhibit pharmacological differences dependent on receptor isoform and host cell environment.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Amylin receptor phenotypes der ...... orm and host cell environment.
@en
type
label
Amylin receptor phenotypes der ...... orm and host cell environment.
@en
prefLabel
Amylin receptor phenotypes der ...... orm and host cell environment.
@en
P2093
P921
P1476
Amylin receptor phenotypes der ...... orm and host cell environment.
@en
P2093
Christopoulos G
Tilakaratne N
P407
P577
2000-07-01T00:00:00Z