about
An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.Structure/function of human herpesvirus-8 MIP-II (1-71) and the antagonist N-terminal segment (1-10)Structure of a pilin monomer from Pseudomonas aeruginosa: implications for the assembly of piliFive atomic resolution structures of endothiapepsin inhibitor complexes: implications for the aspartic proteinase mechanismEvidence for plasticity and structural mimicry at the immunoglobulin light chain-protein L interfaceStructural insights into the interaction of insulin-like growth factor 2 with IGF2R domain 11A mammalian type I fatty acid synthase acyl carrier protein domain does not sequester acyl chainsProbing the Interactions of early polyketide intermediates with the Actinorhodin ACP from S. coelicolor A3(2)Structure and malonyl CoA-ACP transacylase binding of streptomyces coelicolor fatty acid synthase acyl carrier proteinRecognition of intermediate functionality by acyl carrier protein over a complete cycle of fatty acid biosynthesisThe Determinants of Activity and Specificity in Actinorhodin Type II Polyketide KetoreductaseA conserved motif flags acyl carrier proteins for β-branching in polyketide synthesisThe HicA toxin from Burkholderia pseudomallei has a role in persister cell formationSolution structure of the actinorhodin polyketide synthase acyl carrier protein from Streptomyces coelicolor A3(2)Insights into the mechanism of heterodimerization from the 1H-NMR solution structure of the c-Myc-Max heterodimeric leucine zipperSolution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammationEngineering protein stability with atomic precision in a monomeric miniprotein.Kinetics of insulin-like growth factor II (IGF-II) interaction with domain 11 of the human IGF-II/mannose 6-phosphate receptor: function of CD and AB loop solvent-exposed residues.A simple and accessible synthetic lectin for glucose recognition and sensing.Synthesis and evaluation of a desymmetrised synthetic lectin: an approach to carbohydrate receptors with improved versatility.A synthetic lectin for O-linked beta-N-acetylglucosamineSolution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.Design and nuclear magnetic resonance (NMR) structure determination of the second extracellular immunoglobulin tyrosine kinase A (TrkAIg2) domain construct for binding site elucidation in drug discovery.Synthetic Receptors for the High-Affinity Recognition of O-GlcNAc Derivatives.The role of large-scale motions in catalysis by dihydrofolate reductase.Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonistStructure and function of the human Gly1619Arg polymorphism of M6P/IGF2R domain 11 implicated in IGF2 dependent growthConstructing a man-made c-type cytochrome maquette in vivo: electron transfer, oxygen transport and conversion to a photoactive light harvesting maquette.Assembly pathway of a designed alpha-helical protein fiber.Structural determinants of calmodulin binding to the intracellular C-terminal domain of the metabotropic glutamate receptor 7A.Platform Synthetic Lectins for Divalent Carbohydrate Recognition in WaterLocal and macroscopic electrostatic interactions in single α-helices.Construction and in vivo assembly of a catalytically proficient and hyperthermostable de novo enzyme.Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain.Recognition of extended linear and cyclised polyketide mimics by a type II acyl carrier protein.Backbone dynamics of the human CC chemokine eotaxin: fast motions, slow motions, and implications for receptor bindingAffinity enhancement by dendritic side chains in synthetic carbohydrate receptors.Enantioselective carbohydrate recognition by synthetic lectins in water.Elucidation of the relative and absolute stereochemistry of the kalimantacin/batumin antibiotics.Expression, purification and preliminary X-ray diffraction analysis of a ketoreductase from a type II polyketide synthase.
P50
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P50
description
hulumtues
@sq
researcher
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wetenschapper
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հետազոտող
@hy
name
Matthew P. Crump
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Matthew P. Crump
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Matthew P. Crump
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Matthew P. Crump
@nl
Matthew P. Crump
@sl
type
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Matthew P. Crump
@ast
Matthew P. Crump
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Matthew P. Crump
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Matthew P. Crump
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Matthew P. Crump
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M P Crump
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prefLabel
Matthew P. Crump
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Matthew P. Crump
@en
Matthew P. Crump
@es
Matthew P. Crump
@nl
Matthew P. Crump
@sl
P106
P1153
7005419210
P21
P31
P496
0000-0002-7868-5818