Anti-IL-4 treatment prevents dermal collagen deposition in the tight-skin mouse model of scleroderma. - Test2 - elhamkhani - TriplyDB

Anti-IL-4 treatment prevents dermal collagen deposition in the tight-skin mouse model of scleroderma.

Anti-IL-4 treatment prevents dermal collagen deposition in the tight-skin mouse model of scleroderma.

http://www.wikidata.org/entity/Q41005869

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Pharmacotherapy of systemic sclerosis Cellular and molecular mechanisms of fibrosis Leukocytes: The Double-Edged Sword in Fibrosis Host responses in tissue repair and fibrosis Myofibroblasts and lung fibrosis induced by carbon nanotube exposure Mechanisms of fibrosis: therapeutic translation for fibrotic disease T lymphocyte and fibroblast interactions: the case of skin involvement in systemic sclerosis and other examples.Disrupting the IL-4 gene rescues mice homozygous for the tight-skin mutation from embryonic death and diminishes TGF-beta production by fibroblasts B-lymphocyte depletion reduces skin fibrosis and autoimmunity in the tight-skin mouse model for systemic sclerosis Hepatocyte growth factor ameliorates dermal sclerosis in the tight-skin mouse model of scleroderma.Fibrotic disease and the T(H)1/T(H)2 paradigm.Cellular and molecular mechanisms of bleomycin-induced murine scleroderma: current update and future perspective.Cytokine mediated tissue fibrosis T cells in systemic sclerosis: a reappraisal.Role of anti-inflammatory cytokines IL-4 and IL-13 in systemic sclerosis.Potential roles of interleukin-17A in the development of skin fibrosis in mice.Regulatory effect of extracellular signal-regulated kinases (ERK) on type I collagen synthesis in human dermal fibroblasts stimulated by IL-4 and IL-13.PGD2-CRTH2 pathway promotes tubulointerstitial fibrosis.Cigarette smoke exposure potentiates bleomycin-induced lung fibrosis in guinea pigs.Overexpression of OSM and IL-6 impacts the polarization of pro-fibrotic macrophages and the development of bleomycin-induced lung fibrosis.Tumor rejection by modulation of tumor stromal fibroblasts.Bleomycin-induced lung fibrosis in IL-4-overexpressing and knockout mice.Immunomodulation of experimental pulmonary fibrosis by intravenous immunoglobulin (IVIG).Influence of the anti-inflammatory cytokine interleukin-4 on human joint capsule myofibroblasts.Defects in regulatory T cells due to CD28 deficiency induce a qualitative change of allogeneic immune response in chronic graft-versus-host disease.Evaluation of the efficacy and safety of topical imiquimod 5% for plaque-type morphea: a multicenter, prospective, vehicle-controlled trial.

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P2860

Anti-IL-4 treatment prevents dermal collagen deposition in the tight-skin mouse model of scleroderma.

http://www.wikidata.org/entity/Q41005869

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Anti-IL-4 treatment prevents d ...... in mouse model of scleroderma.

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P2860

Cloning and analysis of murine cDNA that encodes a fibrogenic lymphokine, fibrosin

Functional diversity of helper T lymphocytes

Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes.

Acquisition of lymphokine-producing phenotype by CD4+ T cells.

Interleukin 4 expressed in situ selectively alters thymocyte development

Neutralizing antibody to interleukin 4 induces systemic protection and T helper type 1-associated immunity in murine candidiasis

Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism.

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets.

Relationships among antigen presentation, cytokines, immune deviation, and autoimmune disease

Constitutive expression of interleukin (IL)-4 in vivo causes autoimmune-type disorders in mice.

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