about
Evolution of High Cellulolytic Activity in Symbiotic Streptomyces through Selection of Expanded Gene Content and Coordinated Gene ExpressionAn expanded evaluation of protein function prediction methods shows an improvement in accuracyEvolving hard problems: Generating human genetics datasets with a complex etiologyReproducibility of computational workflows is automated using continuous analysisA machine learning classifier trained on cancer transcriptomes detects NF1 inactivation signal in glioblastomaComputational genetics analysis of grey matter density in Alzheimer's disease.Accelerating epistasis analysis in human genetics with consumer graphics hardwareSemi-supervised learning of the electronic health record for phenotype stratification.Multifactor dimensionality reduction for graphics processing units enables genome-wide testing of epistasis in sporadic ALS.Chapter 2: Data-driven view of disease biologyBig data bioinformatics.Adapting bioinformatics curricula for big data.Cross-platform normalization of microarray and RNA-seq data for machine learning applicationsADAGE-Based Integration of Publicly Available Pseudomonas aeruginosa Gene Expression Data with Denoising Autoencoders Illuminates Microbe-Host Interactions.Sci-Hub provides access to nearly all scholarly literatureFailure to replicate a genetic association may provide important clues about genetic architectureIntegrative systems biology for data-driven knowledge discovery.Predicting targeted drug combinations based on Pareto optimal patterns of coexpression network connectivityPILGRM: an interactive data-driven discovery platform for expert biologistsAccurate evaluation and analysis of functional genomics data and methodsFunctional knowledge transfer for high-accuracy prediction of under-studied biological processesSystems level analysis of systemic sclerosis shows a network of immune and profibrotic pathways connected with genetic polymorphisms.Testing multiple hypotheses through IMP weighted FDR based on a genetic functional network with application to a new zebrafish transcriptome studyLeveraging global gene expression patterns to predict expression of unmeasured genesInternational genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways.IMP: a multi-species functional genomics portal for integration, visualization and prediction of protein functions and networks.Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions.Network-based analysis of genetic variants associated with hippocampal volume in Alzheimer's disease: a study of ADNI cohorts.Understanding multicellular function and disease with human tissue-specific networks.LT-IIb(T13I), a non-toxic type II heat-labile enterotoxin, augments the capacity of a ricin toxin subunit vaccine to evoke neutralizing antibodies and protective immunityGenomic characterization of patient-derived xenograft models established from fine needle aspirate biopsies of a primary pancreatic ductal adenocarcinoma and from patient-matched metastatic sitesDefining cell-type specificity at the transcriptional level in human diseaseComprehensive Cross-Population Analysis of High-Grade Serous Ovarian Cancer Supports No More Than Three Subtypes.A novel multi-network approach reveals tissue-specific cellular modulators of fibrosis in systemic sclerosis.Implicating candidate genes at GWAS signals by leveraging topologically associating domains.Targeted exploration and analysis of large cross-platform human transcriptomic compendia.Unsupervised Extraction of Stable Expression Signatures from Public Compendia with an Ensemble of Neural Networks.Tissue-specific network-based genome wide study of amygdala imaging phenotypes to identify functional interaction modules.Genetic Association-Guided Analysis of Gene Networks for the Study of Complex Traits.Pathway and network-based strategies to translate genetic discoveries into effective therapies.
P50
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P50
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Casey S. Greene
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Casey S. Greene
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P1053
L-2057-2015
P106
P1153
12141512300
P2002
GreeneScientist
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P2798
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P3829
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casey-greene
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