Fas induces cytoplasmic apoptotic responses and activation of the MKK7-JNK/SAPK and MKK6-p38 pathways independent of CPP32-like proteases.
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Alternatively spliced products CC3 and TC3 have opposing effects on apoptosisMAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/dual leucine zipper-bearing kinase/leucine zipper protein kinaseInhibition of Daxx-mediated apoptosis by heat shock protein 27Identification and characterization of functional domains in a mixed lineage kinase LZKHuman mitogen-activated protein kinase kinase 7 (MKK7) is a highly conserved c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) activated by environmental stresses and physiological stimuliMixed lineage kinase LZK and antioxidant protein-1 activate NF-kappaB synergisticallyCaspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosisOverexpression of acid ceramidase protects from tumor necrosis factor-induced cell deathSAPK2/p38-dependent F-actin reorganization regulates early membrane blebbing during stress-induced apoptosisThe MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinasesImpaired Akt activity down-modulation, caspase-3 activation, and apoptosis in cells expressing a caspase-resistant mutant of RasGAP at position 157Antiapoptotic signaling generated by caspase-induced cleavage of RasGAP.MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis.p38 mitogen-activated protein kinase mediates the Fas-induced mitochondrial death pathway in CD8+ T cells.Cell volume control and signal transduction in apoptosis.Macrophages resistant to endogenously generated nitric oxide-mediated apoptosis are hypersensitive to exogenously added nitric oxide donors: dichotomous apoptotic response independent of caspase 3 and reversal by the mitogen-activated protein kinaseActivated cytotoxic lymphocytes promote tumor progression by increasing the ability of 3LL tumor cells to mediate MDSC chemoattraction via Fas signaling.Regulation of fas ligand expression during activation-induced cell death in T cells by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase.Nuclear factor-kappa B activation by the CXC chemokine melanoma growth-stimulatory activity/growth-regulated protein involves the MEKK1/p38 mitogen-activated protein kinase pathwayAsymmetric dimethylarginine attenuates serum starvation-induced apoptosis via suppression of the Fas (APO-1/CD95)/JNK (SAPK) pathway.Non-apoptotic signaling pathways activated by soluble Fas ligand in serum-starved human fibroblasts. Mitogen-activated protein kinases and NF-kappaB-dependent gene expression.Involvement of p38 in apoptosis-associated membrane blebbing and nuclear condensation.Uncouplers of oxidative phosphorylation can enhance a Fas death signalInhibition of mitogen-activated kinase signaling sensitizes HeLa cells to Fas receptor-mediated apoptosis.CD95 ligand induces motility and invasiveness of apoptosis-resistant tumor cells.Activation of the c-Jun N-terminal kinase pathway by MST1 is essential and sufficient for the induction of chromatin condensation during apoptosis.Caspase-8- and JNK-dependent AP-1 activation is required for Fas ligand-induced IL-8 production.Keratins modulate c-Flip/extracellular signal-regulated kinase 1 and 2 antiapoptotic signaling in simple epithelial cells.Induction of apoptosis in vascular smooth muscle cells by mechanical stretch.X protein of hepatitis B virus inhibits Fas-mediated apoptosis and is associated with up-regulation of the SAPK/JNK pathway.Activation of the luteinizing hormone beta promoter by gonadotropin-releasing hormone requires c-Jun NH2-terminal protein kinase.p38 mitogen-activated protein kinase regulates a novel, caspase-independent pathway for the mitochondrial cytochrome c release in ultraviolet B radiation-induced apoptosis.Role of caspases and possible involvement of retinoblastoma protein during TGFbeta-mediated apoptosis of human B lymphocytes.TRAIL/Apo2L activates c-Jun NH2-terminal kinase (JNK) via caspase-dependent and caspase-independent pathways.JNK (c-Jun N-terminal kinase) and p38 activation in receptor-mediated and chemically-induced apoptosis of T-cells: differential requirements for caspase activation.Inhibition of homodimerization of poly(ADP-ribose) polymerase by its C-terminal cleavage products produced during apoptosis.p38 MAP kinase negatively regulates cyclin D1 expression in airway smooth muscle cells.Activation of SAPK/JNK by camptothecin sensitizes androgen-independent prostate cancer cells to Fas-induced apoptosis.The activation of c-Jun NH2-terminal kinase (JNK) by DNA-damaging agents serves to promote drug resistance via activating transcription factor 2 (ATF2)-dependent enhanced DNA repair.
P2860
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P2860
Fas induces cytoplasmic apoptotic responses and activation of the MKK7-JNK/SAPK and MKK6-p38 pathways independent of CPP32-like proteases.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Fas induces cytoplasmic apopto ...... ndent of CPP32-like proteases.
@en
type
label
Fas induces cytoplasmic apopto ...... ndent of CPP32-like proteases.
@en
prefLabel
Fas induces cytoplasmic apopto ...... ndent of CPP32-like proteases.
@en
P2860
P356
P1476
Fas induces cytoplasmic apopto ...... endent of CPP32-like proteases
@en
P2093
F Toyoshima
P2860
P304
P356
10.1083/JCB.139.4.1005
P407
P577
1997-11-01T00:00:00Z