Non-cleavable talin rescues defect in the T-cell conjugation of T-cells deficient in the immune adaptor SKAP1.

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D120 and K152 within the PH Domain of T Cell Adapter SKAP55 Regulate Plasma Membrane Targeting of SKAP55 and LFA-1 Affinity Modulation in Human T Lymphocytes.LFA-1 activates focal adhesion kinases FAK1/PYK2 to generate LAT-GRB2-SKAP1 complexes that terminate T-cell conjugate formation

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Non-cleavable talin rescues defect in the T-cell conjugation of T-cells deficient in the immune adaptor SKAP1.

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http://www.wikidata.org/entity/Q41175115

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

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name

Non-cleavable talin rescues de ...... t in the immune adaptor SKAP1.

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type

Item

label

Non-cleavable talin rescues de ...... t in the immune adaptor SKAP1.

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Non-cleavable talin rescues de ...... t in the immune adaptor SKAP1.

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Non-cleavable talin rescues de ...... t in the immune adaptor SKAP1.

@en

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Christopher E Rudd

http://www.w3.org/2001/XMLSchema#string

Daina Lim

http://www.w3.org/2001/XMLSchema#string

Yuning Lu

http://www.w3.org/2001/XMLSchema#string

P2860

FYN-T-FYB-SLP-76 interactions define a T-cell receptor zeta/CD3-mediated tyrosine phosphorylation pathway that up-regulates interleukin 2 transcription in T-cells

Structural determinants of integrin recognition by talin

Structural basis of integrin activation by talin

Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion

RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

Regulation of Vav-SLP-76 binding by ZAP-70 and its relevance to TCR zeta/CD3 induction of interleukin-2

Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle

An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55R

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

A new protein of adhesion plaques and ruffling membranes

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40-46

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scholarly article

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10.1016/J.IMLET.2016.02.004

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172

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P577

2016-02-18T00:00:00Z

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26905930

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P932

4860717

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Non-cleavable talin rescues defect in the T-cell conjugation of T-cells deficient in the immune adaptor SKAP1.

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P2860

P2860

Non-cleavable talin rescues defect in the T-cell conjugation of T-cells deficient in the immune adaptor SKAP1.

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P1476

P2093

P2860

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P698

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P2860

P304

P31

P356

P478

P577

P698

P932