MUC1-C activates EZH2 expression and function in human cancer cells.

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MUC1-C activates polycomb repressive complexes and downregulates tumor suppressor genes in human cancer cells.MUC1-C Induces PD-L1 and Immune Evasion in Triple-Negative Breast Cancer.Epigenetic Contribution of High-Mobility Group A Proteins to Stem Cell Properties.

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MUC1-C activates EZH2 expression and function in human cancer cells.

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http://www.wikidata.org/entity/Q41286875

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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2017年學術文章

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name

MUC1-C activates EZH2 expression and function in human cancer cells.

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type

Item

label

MUC1-C activates EZH2 expression and function in human cancer cells.

@en

prefLabel

MUC1-C activates EZH2 expression and function in human cancer cells.

@en

P1476

MUC1-C activates EZH2 expression and function in human cancer cells

@en

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Ashujit Tagde

http://www.w3.org/2001/XMLSchema#string

Audrey Bouillez

http://www.w3.org/2001/XMLSchema#string

Camilla L Christensen

http://www.w3.org/2001/XMLSchema#string

Hasan Rajabi

http://www.w3.org/2001/XMLSchema#string

Kwok-Kin Wong

http://www.w3.org/2001/XMLSchema#string

Maroof Alam

http://www.w3.org/2001/XMLSchema#string

Masayuki Hiraki

http://www.w3.org/2001/XMLSchema#string

Mehmet Samur

http://www.w3.org/2001/XMLSchema#string

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The Polycomb group protein EZH2 directly controls DNA methylation

MUC1-C oncoprotein activates ERK→C/EBPβ signaling and induction of aldehyde dehydrogenase 1A1 in breast cancer cells

Mucins in cancer: function, prognosis and therapy

EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

Targeting EZH2 in cancer

Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin.

SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex

MUC1 oncoprotein blocks glycogen synthase kinase 3beta-mediated phosphorylation and degradation of beta-catenin

MYC stimulates EZH2 expression by repression of its negative regulator miR-26a

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s41598-017-07850-0

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scholarly article

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10.1038/S41598-017-07850-0

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English

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Donald Kufe

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2017-08-07T00:00:00Z

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28785086

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P932

5547076

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MUC1-C activates EZH2 expression and function in human cancer cells.

about

P2860

P2860

MUC1-C activates EZH2 expression and function in human cancer cells.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932