Intermolecular epistasis shaped the function and evolution of an ancient transcription factor and its DNA binding sites.
about
Detecting High-Order Epistasis in Nonlinear Genotype-Phenotype MapsEvolving new protein-protein interaction specificity through promiscuous intermediates.Resurrecting ancestral structural dynamics of an antiviral immune receptor: adaptive binding pocket reorganization repeatedly shifts RNA preference.High-order epistasis shapes evolutionary trajectories.Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space.Epistasis in protein evolution.Bridging the physical scales in evolutionary biology: from protein sequence space to fitness of organisms and populations.Reconstructing Ancient Proteins to Understand the Causes of Structure and Function.Regulatory network structure determines patterns of intermolecular epistasis.Alternative evolutionary histories in the sequence space of an ancient protein.Robustness of Reconstructed Ancestral Protein Functions to Statistical Uncertainty.Unravelling the Carbohydrate-Binding Preferences of the Carbohydrate-Binding Modules of AMP-Activated Protein Kinase.Complex selection on a regulator of social cognition: Evidence of balancing selection, regulatory interactions and population differentiation in the prairie vole Avpr1a locus.Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima.Mapping the Evolutionary Potential of RNA Viruses.The Influence of Higher-Order Epistasis on Biological Fitness Landscape Topography.Evolution of complex adaptations in molecular systems.RNA-mediated gene regulation is less evolvable than transcriptional regulation.
P2860
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P2860
Intermolecular epistasis shaped the function and evolution of an ancient transcription factor and its DNA binding sites.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Intermolecular epistasis shape ...... tor and its DNA binding sites.
@en
type
label
Intermolecular epistasis shape ...... tor and its DNA binding sites.
@en
prefLabel
Intermolecular epistasis shape ...... tor and its DNA binding sites.
@en
P2093
P2860
P356
P1433
P1476
Intermolecular epistasis shape ...... tor and its DNA binding sites.
@en
P2093
Alesia N McKeown
Dave W Anderson
Joseph W Thornton
P2860
P304
P356
10.7554/ELIFE.07864
P407
P577
2015-06-15T00:00:00Z