Glucose, other secretagogues, and nerve growth factor stimulate mitogen-activated protein kinase in the insulin-secreting beta-cell line, INS-1.
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Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascadeActivation of mitogen-activating protein kinase by glucose is not required for insulin secretionRole of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expressionSignaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cellsExpression of cAMP-regulated guanine nucleotide exchange factors in pancreatic beta-cells.The expression and function of a group VIA calcium-independent phospholipase A2 (iPLA2beta) in beta-cellscAMP-regulated guanine nucleotide exchange factor II (Epac2) mediates Ca2+-induced Ca2+ release in INS-1 pancreatic beta-cellsGLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cellsSignal transduction of pregnenolone sulfate in insulinoma cells: activation of Egr-1 expression involving TRPM3, voltage-gated calcium channels, ERK, and ternary complex factorsTRPM4 controls insulin secretion in pancreatic beta-cellsPim3 negatively regulates glucose-stimulated insulin secretionGeneration and characterization of human insulin-releasing cell lines.Protein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells.Small G proteins in islet beta-cell function.The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes.Xenin-25 potentiates glucose-dependent insulinotropic polypeptide action via a novel cholinergic relay mechanism.Insulinotropic toxins as molecular probes for analysis of glucagon-likepeptide-1 receptor-mediated signal transduction in pancreatic beta-cells.Quercetin potentiates insulin secretion and protects INS-1 pancreatic β-cells against oxidative damage via the ERK1/2 pathway.High glucose predisposes gene expression and ERK phosphorylation to apoptosis and impaired glucose-stimulated insulin secretion via the cytoskeletonNovel role for matricellular proteins in the regulation of islet β cell survival: the effect of SPARC on survival, proliferation, and signaling.Calcineurin increases glucose activation of ERK1/2 by reversing negative feedback.Glucagon-like peptide 1 stimulates insulin gene promoter activity by protein kinase A-independent activation of the rat insulin I gene cAMP response element.Exendin-4 Prevents Vascular Smooth Muscle Cell Proliferation and Migration by Angiotensin II via the Inhibition of ERK1/2 and JNK Signaling Pathways.Differential regulation of CHOP-10/GADD153 gene expression by MAPK signaling in pancreatic beta-cells.Pancreatic beta cells synthesize and secrete nerve growth factorOn the role of IRS2 in the regulation of functional beta-cell mass.Nutrigenomics, beta-cell function and type 2 diabetesBeta cells in type 2 diabetes - a crucial contribution to pathogenesis.Glucose and GLP-1 stimulate cAMP production via distinct adenylyl cyclases in INS-1E insulinoma cells.Chromatin-bound mitogen-activated protein kinases transmit dynamic signals in transcription complexes in beta-cells.Estrogens directly potentiate neuronal L-type Ca2+ channels.The roles of MAPKs in disease.Genetic and Molecular Basis of QTL of Diabetes in Mouse: Genes and PolymorphismsEarly growth response factor-1 mediates insulin-inducible vascular endothelial cell proliferation and regrowth after injury.Glucose activates mitogen-activated protein kinase (extracellular signal-regulated kinase) through proline-rich tyrosine kinase-2 and the Glut1 glucose transporter.GRFbeta, a novel regulator of calcium signaling, is expressed in pancreatic beta cells and brain.Loss of Egr-1 sensitizes pancreatic β-cells to palmitate-induced ER stress and apoptosis.Rat pancreatic level of cystathionine γ-lyase is regulated by glucose level via specificity protein 1 (SP1) phosphorylation.High-glucose stimulation increases reactive oxygen species production through the calcium and mitogen-activated protein kinase-mediated activation of mitochondrial fissionbeta-Arrestin 1 is required for PAC1 receptor-mediated potentiation of long-lasting ERK1/2 activation by glucose in pancreatic beta-cells.
P2860
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P2860
Glucose, other secretagogues, and nerve growth factor stimulate mitogen-activated protein kinase in the insulin-secreting beta-cell line, INS-1.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Glucose, other secretagogues, ...... creting beta-cell line, INS-1.
@en
type
label
Glucose, other secretagogues, ...... creting beta-cell line, INS-1.
@en
prefLabel
Glucose, other secretagogues, ...... creting beta-cell line, INS-1.
@en
P2093
P356
P1476
Glucose, other secretagogues, ...... ecreting beta-cell line, INS-1
@en
P2093
C B Wollheim
E Van Obberghen
P304
P356
10.1074/JBC.270.14.7882
P407
P577
1995-04-01T00:00:00Z