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RNA-seq identifies clinically relevant fusion genes in leukemia including a novel MEF2D/CSF1R fusion responsive to imatinib.Fusion of the MORF and CBP genes in acute myeloid leukemia with the t(10;16)(q22;p13)Rearrangement of the transcription factor gene CHOP in myxoid liposarcomas with t(12;16)(q13;p11)CRK proto-oncogene maps to human chromosome band 17p13Expression patterns of the human sarcoma-associated genes FUS and EWS and the genomic structure of FUSIsodicentric 7p, idic(7)(q11.2), in acute myeloid leukemia associated with older age and favorable response to induction chemotherapy: a new clinical entity?Recurrent and multiple bladder tumors show conserved expression profilesGene expression signatures in childhood acute leukemias are largely unique and distinct from those of normal tissues and other malignancies.Integrative analysis of gene expression and copy number alterations using canonical correlation analysis.The breakpoint region of the most common isochromosome, i(17q), in human neoplasia is characterized by a complex genomic architecture with large, palindromic, low-copy repeatsMolecular signatures in childhood acute leukemia and their correlations to expression patterns in normal hematopoietic subpopulations.The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemiasDeregulation of cyclin D2 by juxtaposition with T-cell receptor alpha/delta locus in t(12;14)(p13;q11)-positive childhood T-cell acute lymphoblastic leukemia.Cytogenetic and molecular genetic evolution of chronic myeloid leukemia.Tiling resolution array comparative genomic hybridization, expression and methylation analyses of dup(1q) in Burkitt lymphomas and pediatric high hyperdiploid acute lymphoblastic leukemias reveal clustered near-centromeric breakpoints and overexpresModeling chronic myeloid leukemia in immunodeficient mice reveals expansion of aberrant mast cells and accumulation of pre-B cells.Activation of human telomerase reverse transcriptase through gene fusion in clear cell sarcoma of the kidney.Deep sequencing and SNP array analyses of pediatric T-cell acute lymphoblastic leukemia reveal NOTCH1 mutations in minor subclones and a high incidence of uniparental isodisomies affecting CDKN2AEbf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiencyAntibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.A glioma classification scheme based on coexpression modules of EGFR and PDGFRA.Pancreatic carcinoma cell lines with SMAD4 inactivation show distinct expression responses to TGFB1.Trisomy 8 as the sole chromosomal aberration in myelocytic malignancies: a multicolor and locus-specific fluorescence in situ hybridization study.Multicolor COBRA-FISH analysis of chronic myeloid leukemia reveals novel cryptic balanced translocations during disease progression.The emerging complexity of gene fusions in cancer.Threshold-free high-power methods for the ontological analysis of genome-wide gene-expression studies.An improved method for detecting and delineating genomic regions with altered gene expression in cancer.Whole-exome sequencing of pediatric acute lymphoblastic leukemia.Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice.Deregulation of the Wilms' tumour gene 1 protein (WT1) by BCR/ABL1 mediates resistance to imatinib in human leukaemia cells.Gene expression profiling of leukemic cell lines reveals conserved molecular signatures among subtypes with specific genetic aberrations.An EcoRI polymorphism at the insulin receptor locus on a fragment comprising exons 4 to 8.Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer.Regional localization and developmental expression of the BCR gene in rodent brain.Genetic analysis of dasatinib-treated chronic myeloid leukemia rapidly developing into acute myeloid leukemia with monosomy 7 in Philadelphia-negative cells.Acute myelomonocytic leukemia with inv(16)(p13q22) complicating Philadelphia chromosome positive chronic myeloid leukemia.Prognostic implications of BCL6 rearrangement in uniformly treated patients with diffuse large B-cell lymphoma--a Nordic Lymphoma Group study.Fusion of the BCR and the fibroblast growth factor receptor-1 (FGFR1) genes as a result of t(8;22)(p11;q11) in a myeloproliferative disorder: the first fusion gene involving BCR but not ABL.Clinical and genetic studies of ETV6/ABL1-positive chronic myeloid leukaemia in blast crisis treated with imatinib mesylate.Establishment and phenotypic characterization of human U937 cells with inducible P210 BCR/ABL expression reveals upregulation of CEACAM1 (CD66a).
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P50
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հետազոտող
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Thoas Fioretos
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Thoas Michael Fioretos
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Thoas Michael Fioretos
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Thoas Fioretos
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P106
P108
P2038
Thoas_Fioretos
P21
P31
P496
0000-0002-3235-6154
P569
1962-05-04T00:00:00Z