Expression cloning and signaling properties of the rat glucagon receptor.
about
Prototypic G protein-coupled receptor for the intestinotrophic factor glucagon-like peptide 2Expression of two human skeletal calcitonin receptor isoforms cloned from a giant cell tumor of bone. The first intracellular domain modulates ligand binding and signal transductionCloning and functional characterization of a third pituitary adenylate cyclase-activating polypeptide receptor subtype expressed in insulin-secreting cellsMolecular basis for negative regulation of the glucagon receptorCalcitonin and calcitonin receptors: bone and beyondCalcitonin receptor gene expression in K562 chronic myelogenous leukemic cellsLow doses of bisphenol A and diethylstilbestrol impair Ca2+ signals in pancreatic alpha-cells through a nonclassical membrane estrogen receptor within intact islets of Langerhans.Overexpression of membrane proteins in mammalian cells for structural studiesStructure-function of the glucagon receptor family of G protein-coupled receptors: the glucagon, GIP, GLP-1, and GLP-2 receptorsSignal transduction of the GLP-1-receptor cloned from a human insulinomaLower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout miceVstm3 is a member of the CD28 family and an important modulator of T-cell functionAlpha-latrotoxin receptor, latrophilin, is a novel member of the secretin family of G protein-coupled receptorsMutations in the second cytoplasmic loop of the rat parathyroid hormone (PTH)/PTH-related protein receptor result in selective loss of PTH-stimulated phospholipase C activityMelatonin influences insulin secretion primarily via MT(1) receptors in rat insulinoma cells (INS-1) and mouse pancreatic isletsAntibodies against specific extracellular epitopes of the glucagon receptor block glucagon bindingMolecular cloning of a novel variant of the pituitary adenylate cyclase-activating polypeptide (PACAP) receptor that stimulates calcium influx by activation of L-type calcium channelsThe glucagon receptor is required for the adaptive metabolic response to fastingA cDNA encoding the calcitonin gene-related peptide type 1 receptorPancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and massIdentification of a glucose response element in the promoter of the rat glucagon receptor gene.Reproducible production of a PEGylated dual-acting peptide for diabetesBiologic properties and therapeutic potential of glucagon-like peptide-2.Glucagon receptor activates extracellular signal-regulated protein kinase 1/2 via cAMP-dependent protein kinase.Liver-specific overexpression of pancreatic-derived factor (PANDER) induces fasting hyperglycemia in miceCloning and characterization of the signal transduction of four splice variants of the human pituitary adenylate cyclase activating polypeptide receptor. Evidence for dual coupling to adenylate cyclase and phospholipase C.Proglucagon-derived peptides: mechanisms of action and therapeutic potential.Ability of various bombesin receptor agonists and antagonists to alter intracellular signaling of the human orphan receptor BRS-3.CD38-mediated Ca(2+) signaling contributes to glucagon-induced hepatic gluconeogenesis.Structural Mapping and Functional Characterization of Zebrafish Class B G-Protein Coupled Receptor (GPCR) with Dual Ligand Selectivity towards GLP-1 and GlucagonGlucagon receptors: effect of exercise and fasting.Targeting glucagon receptor signalling in treating metabolic syndrome and renal injury in Type 2 diabetes: theory versus promiseCa2+ inhibition of type III adenylyl cyclase in vivo.Molecular cloning and expression of a cDNA encoding a receptor for pituitary adenylate cyclase activating polypeptide (PACAP).Insulin-like stimulation of cardiac fuel metabolism by physiological levels of glucagon: involvement of PI3K but not cAMPConverting parathyroid hormone-related peptide (PTHrP) into a potent PTH-2 receptor agonist.An islet-cell protein tyrosine phosphatase is a likely precursor to the 37-kDa autoantigen in type 1 diabetes: human and macaque sequences, tissue distribution, unique and shared epitopes, and predictive autoantibodies.Alterations of epinephrine-induced gluconeogenesis in aging.Current insights and new perspectives on the roles of hyperglucagonemia in non-insulin-dependent type 2 diabetes.Benefits and limitations of reducing glucagon action for the treatment of type 2 diabetes.
P2860
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P2860
Expression cloning and signaling properties of the rat glucagon receptor.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Expression cloning and signaling properties of the rat glucagon receptor.
@en
type
label
Expression cloning and signaling properties of the rat glucagon receptor.
@en
prefLabel
Expression cloning and signaling properties of the rat glucagon receptor.
@en
P2093
P356
P1433
P1476
Expression cloning and signaling properties of the rat glucagon receptor.
@en
P2093
Jelinek LJ
Kuijper JL
Rosenberg GB
Sheppard PO
Sprecher CA
P304
P356
10.1126/SCIENCE.8384375
P407
P577
1993-03-01T00:00:00Z