Structure of a spliceosome remodelled for exon ligation.
about
Crystal structure of U2 snRNP SF3b components: Hsh49p in complex with Cus1p-binding domain.Electron Bio-Imaging Centre (eBIC): the UK national research facility for biological electron microscopy.Structural studies of the endogenous spliceosome - The supraspliceosome.RNA and Proteins: Mutual Respect.Yeast Prp2 liberates the 5' splice site and the branch site adenosine for catalysis of pre-mRNA splicing.Structure determination of group II introns.Methodologies for studying the spliceosome's RNA dynamics with single-molecule FRET.Structural toggle in the RNaseH domain of Prp8 helps balance splicing fidelity and catalytic efficiency.Genetics and biochemistry remain essential in the structural era of the spliceosome.Splicing Factor Mutations in Myelodysplasias: Insights from Spliceosome Structures.Structural basis for activation of an archaeal ribonuclease P RNA by protein cofactors.Structure of a pre-catalytic spliceosome.A close-up look at the spliceosome, at last.Structure of the yeast spliceosomal postcatalytic P complex.Cryo-electron microscopy snapshots of the spliceosome: structural insights into a dynamic ribonucleoprotein machine.Structure of a human catalytic step I spliceosome.Development of an in vitro pre-mRNA splicing assay using plant nuclear extract.Postcatalytic spliceosome structure reveals mechanism of 3'-splice site selection.New windows into retroviral RNA structures.Stress-induced Pseudouridylation Alters the Structural Equilibrium of Yeast U2 snRNA Stem II.Mechanistic insights into precursor messenger RNA splicing by the spliceosome.The conserved AU dinucleotide at the 5' end of nascent U1 snRNA is optimized for the interaction with nuclear cap-binding-complex.Nineteen complex-related factor Prp45 is required for the early stages of cotranscriptional spliceosome assembly.The life of U6 small nuclear RNA, from cradle to grave.Structure of the human activated spliceosome in three conformational states.Insights from structures of cancer-relevant pre-mRNA splicing factors.Intrinsically Disordered Protein Ntr2 Modulates the Spliceosomal RNA Helicase Brr2.Splicing and transcription touch base: co-transcriptional spliceosome assembly and function.Prp8 positioning of U5 snRNA is linked to 5' splice site recognition.Crystal structure of the spliceosomal DEAH-box ATPase Prp2.Structural basis for the second step of group II intron splicing
P2860
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P2860
Structure of a spliceosome remodelled for exon ligation.
description
2017 nî lūn-bûn
@nan
2017年の論文
@ja
2017年論文
@yue
2017年論文
@zh-hant
2017年論文
@zh-hk
2017年論文
@zh-mo
2017年論文
@zh-tw
2017年论文
@wuu
2017年论文
@zh
2017年论文
@zh-cn
name
Structure of a spliceosome remodelled for exon ligation.
@en
type
label
Structure of a spliceosome remodelled for exon ligation.
@en
prefLabel
Structure of a spliceosome remodelled for exon ligation.
@en
P2093
P2860
P50
P356
P1433
P1476
Structure of a spliceosome remodelled for exon ligation.
@en
P2093
Andrew J Newman
Kiyoshi Nagai
Max E Wilkinson
Sebastian M Fica
P2860
P2888
P304
P356
10.1038/NATURE21078
P407
P577
2017-01-11T00:00:00Z
P6179
1029605771