about
Functional characterization of three novel tissue-specific anion exchangers SLC26A7, -A8, and -A9Ultraviolet B radiation regulates cysteine-rich protein 1 in human keratinocytesIdentification of C7orf11 (TTDN1) gene mutations and genetic heterogeneity in nonphotosensitive trichothiodystrophy.The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosusDownstream target genes of the neuropeptide S-NPSR1 pathwayIdentification of MAMDC1 as a candidate susceptibility gene for systemic lupus erythematosus (SLE)IL23R in the Swedish, Finnish, Hungarian and Italian populations: association with IBD and psoriasis, and linkage to celiac diseaseCCHCR1 is up-regulated in skin cancer and associated with EGFR expression.Polymorphisms of the ITGAM gene confer higher risk of discoid cutaneous than of systemic lupus erythematosusCoding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus.Epilysin (MMP-28) expression is associated with cell proliferation during epithelial repair.Matrix metalloproteinase-21, the human orthologue for XMMP, is expressed during fetal development and in cancer.HCR, a candidate gene for psoriasis, is expressed differently in psoriasis and other hyperproliferative skin disorders and is downregulated by interferon-gamma in keratinocytes.Matrix metalloproteinase-21 is expressed epithelially during development and in cancer and is up-regulated by transforming growth factor-beta1 in keratinocytes.Transgenic mouse models support HCR as an effector gene in the PSORS1 locus.Matrix metalloproteinases 21 and 26 are differentially expressed in esophageal squamous cell cancer.MMP-21 is expressed by macrophages and fibroblasts in vivo and in culture.The CCHCR1 (HCR) gene is relevant for skin steroidogenesis and downregulated in cultured psoriatic keratinocytes.Increased expression of matrix metalloproteinases-21 and -26 and TIMP-4 in pancreatic adenocarcinoma.The PSORS1 locus gene CCHCR1 affects keratinocyte proliferation in transgenic mice.The gut-skin axis.Matrix metalloproteinases in the restorative proctocolectomy pouch of pediatric ulcerative colitisIncreased expression of beta6-integrin in skin leads to spontaneous development of chronic wounds.Expression of MMP-10, MMP-21, MMP-26, and MMP-28 in Merkel cell carcinoma.Matrix metalloproteinase-21 expression is associated with keratinocyte differentiation and upregulated by retinoic acid in HaCaT cells.Expression of allograft inflammatory factor-1 in inflammatory skin disorders.MMP-21 is upregulated at early stages of melanoma progression but disappears with more aggressive phenotype.Matrilysin-2 (matrix metalloproteinase-26) is upregulated in keratinocytes during wound repair and early skin carcinogenesis.
P50
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P50
description
onderzoeker
@nl
name
Ulpu Saarialho-Kere
@ast
Ulpu Saarialho-Kere
@en
Ulpu Saarialho-Kere
@es
Ulpu Saarialho-Kere
@sl
type
label
Ulpu Saarialho-Kere
@ast
Ulpu Saarialho-Kere
@en
Ulpu Saarialho-Kere
@es
Ulpu Saarialho-Kere
@sl
prefLabel
Ulpu Saarialho-Kere
@ast
Ulpu Saarialho-Kere
@en
Ulpu Saarialho-Kere
@es
Ulpu Saarialho-Kere
@sl
P106
P21
P31
P569
2000-01-01T00:00:00Z