The 2-His-1-carboxylate facial triad--an emerging structural motif in mononuclear non-heme iron(II) enzymes.
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FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factorCharacterization of patient mutations in human persulfide dioxygenase (ETHE1) involved in H2S catabolismSpectroscopic and magnetic studies of wild-type and mutant forms of the Fe(II)- and 2-oxoglutarate-dependent decarboxylase ALKBH4The sulphur oxygenase reductase from Acidianus ambivalens is a multimeric protein containing a low-potential mononuclear non-haem iron centreMechanism of aromatic amino acid hydroxylationInsights into the catalytic mechanisms of phenylalanine and tryptophan hydroxylase from kinetic isotope effects on aromatic hydroxylationThe DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenasesPhylogenomic identification of five new human homologs of the DNA repair enzyme AlkBStructural studies on the reaction of isopenicillin N synthase with the substrate analogue delta-(l-alpha-aminoadipoyl)-l-cysteinyl-d-alpha-aminobutyrateThe structural basis of cephalosporin formation in a mononuclear ferrous enzymeCrystal Structures of Fe2+ Dioxygenase Superoxo, Alkylperoxo, and Bound Product IntermediatesSwapping metals in Fe- and Mn-dependent dioxygenases: Evidence for oxygen activation without a change in metal redox stateStructural Analysis of an Open Active Site Conformation of Nonheme Iron Halogenase CytC3Crystal structure of Tpa1 from Saccharomyces cerevisiae, a component of the messenger ribonucleoprotein complexA hyperactive cobalt-substituted extradiol-cleaving catechol dioxygenaseIsopenicillin N synthase binds δ-(L-α-aminoadipoyl)-L-cysteinyl-D-thia-allo-isoleucine through both sulfur atomsAzurin as a Protein Scaffold for a Low-coordinate Nonheme Iron Site with a Small-molecule Binding PocketQuaternary ammonium oxidative demethylation: X-ray crystallographic, resonance Raman, and UV-visible spectroscopic analysis of a Rieske-type demethylaseMolecular insight into bacterial cleavage of oceanic dimethylsulfoniopropionate into dimethyl sulfide.The crystal structure of an isopenicillin N synthase complex with an ethereal substrate analogue reveals water in the oxygen binding siteCloR, a bifunctional non-heme iron oxygenase involved in clorobiocin biosynthesisThe putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3Catalytic Mechanisms of Fe(II)- and 2-Oxoglutarate-dependent OxygenasesMetal ions-stimulated iron oxidation in hydroxylases facilitates stabilization of HIF-1 alpha proteinDivergent non-heme iron enzymes in the nogalamycin biosynthetic pathwayImposing function down a (cupin)-barrel: secondary structure and metal stereochemistry in the αKG-dependent oxygenases.The interactions in the carboxyl terminus of human 4-hydroxyphenylpyruvate dioxygenase are critical to mediate the conformation of the final helix and the tail to shield the active site for catalysis.Dke1--structure, dynamics, and function: a theoretical and experimental study elucidating the role of the binding site shape and the hydrogen-bonding network in catalysis.Oxygen requirement for the biosynthesis of the S-2-hydroxymyristate moiety in Salmonella typhimurium lipid A. Function of LpxO, A new Fe2+/alpha-ketoglutarate-dependent dioxygenase homologue.Mutation of the five conserved histidines in the endothelial nitric-oxide synthase hemoprotein domain. No evidence for a non-heme metal requirement for catalysis.Calorimetric assessment of Fe(2+) binding to α-ketoglutarate/taurine dioxygenase: ironing out the energetics of metal coordination by the 2-His-1-carboxylate facial triad.Molecular Dynamics Simulation of Nitrobenzene Dioxygenase Using AMBER Force FieldOxidative decarboxylation of alpha-hydroxy acids by a functional model of the nonheme iron oxygenase, CloR.SyrB2 in syringomycin E biosynthesis is a nonheme FeII alpha-ketoglutarate- and O2-dependent halogenaseAn unusual oxygen-sensitive, iron- and zinc-containing alcohol dehydrogenase from the hyperthermophilic archaeon Pyrococcus furiosusSubstrate specificity of naphthalene dioxygenase: effect of specific amino acids at the active site of the enzyme.Trapping and spectroscopic characterization of an FeIII-superoxo intermediate from a nonheme mononuclear iron-containing enzyme.Spectroscopic and computational investigation of iron(III) cysteine dioxygenase: implications for the nature of the putative superoxo-Fe(III) intermediate.Structural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.A conserved acidic residue in phenylalanine hydroxylase contributes to cofactor affinity and catalysis.
P2860
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P2860
The 2-His-1-carboxylate facial triad--an emerging structural motif in mononuclear non-heme iron(II) enzymes.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
The 2-His-1-carboxylate facial ...... ear non-heme iron(II) enzymes.
@en
type
label
The 2-His-1-carboxylate facial ...... ear non-heme iron(II) enzymes.
@en
prefLabel
The 2-His-1-carboxylate facial ...... ear non-heme iron(II) enzymes.
@en
P1433
P1476
The 2-His-1-carboxylate facial ...... ear non-heme iron(II) enzymes.
@en
P304
P356
10.1111/J.1432-1033.1997.T01-1-00625.X
P407
P577
1997-12-01T00:00:00Z