Amino acid substitutions in the N-terminal segment of cystatin C create selective protein inhibitors of lysosomal cysteine proteinases.
about
Functional aspects of the human salivary cystatins in the oral environmentHydrophobic sequences can substitute for the wild-type N-terminal sequence of cystatin A (stefin A) in tight binding to cysteine proteinases selection of high-affinity N-terminal region variants by phage display.Viral cystatin evolution and three-dimensional structure modelling: a case of directional selection acting on a viral protein involved in a host-parasitoid interaction.Cystatin C increases in cardiac injury: a role in extracellular matrix protein modulationBiochemistry and clinical role of human cystatin C.Crystal structure of human cystatin D, a cysteine peptidase inhibitor with restricted inhibition profile.Salivary (SD-type) cystatins: over one billion years in the making--but to what purpose?Modulating the proteinase inhibitory profile of a plant cystatin by single mutations at positively selected amino acid sites.Single substitutions to closely related amino acids contribute to the functional diversification of an insect-inducible, positively selected plant cystatin.Characterization of a cysteine proteinase inhibitor induced during neuronal cell differentiation.Cystatin C protects neuronal cells against mutant copper-zinc superoxide dismutase-mediated toxicity.Overexpression of cystatin C in synovium does not reduce synovitis or cartilage degradation in established osteoarthritis.Tailoring the specificity of a plant cystatin toward herbivorous insect digestive cysteine proteases by single mutations at positively selected amino acid sites.Specific cysteine protease inhibitors act as deterrents of western flower thrips, Frankliniella occidentalis (Pergande), in transgenic potato.
P2860
Q28144253-70B0BFB0-566F-4300-A39B-C409DF30B9D7Q30674379-2666D728-0F5C-467D-B354-A889C0AD7DDEQ33368470-21DBD171-3DE6-4E60-AB11-0312576E761CQ34062726-D241E95B-FF39-4BE6-A010-86D0FA784A76Q34377103-AE2A6885-785D-4D7B-B43C-5A562F6C7A18Q34397220-D14D9B0F-E538-4C5D-AE2A-BDCF9CA5B0C7Q35033473-D80D9562-7F17-479B-8578-CCBA91EA0EECQ38309782-8037448E-5AEB-4BDD-9775-D145490F4552Q40034616-14EC63C7-7CAF-47C5-B7A2-367E23A2B7D6Q40725030-97673EAB-F3A4-416A-806F-DE4FBBFD9951Q41832100-E794D0FC-7FFC-479D-B142-276B7AAE98EBQ41927532-C6EE2427-8FBA-49A3-A283-5C1878F360F3Q46810182-9CFB2C5C-4EF5-4E69-807D-5C859BD8A937Q51773599-279BEAE7-360F-4606-9BBA-DF51EE1B4EDD
P2860
Amino acid substitutions in the N-terminal segment of cystatin C create selective protein inhibitors of lysosomal cysteine proteinases.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Amino acid substitutions in th ...... ysosomal cysteine proteinases.
@en
type
label
Amino acid substitutions in th ...... ysosomal cysteine proteinases.
@en
prefLabel
Amino acid substitutions in th ...... ysosomal cysteine proteinases.
@en
P2093
P2860
P356
P1433
P1476
Amino acid substitutions in th ...... ysosomal cysteine proteinases.
@en
P2093
Abrahamson M
Sol-Church K
P2860
P304
P356
10.1042/BJ3300833
P407
P478
330 ( Pt 2)
P577
1998-03-01T00:00:00Z