about
Differential effects of the Gβ5-RGS7 complex on muscarinic M3 receptor-induced Ca2+ influx and release.The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers.Helix 8 and the i3 loop of the muscarinic M3 receptor are crucial sites for its regulation by the Gβ5-RGS7 complex.BET bromodomain proteins are required for glioblastoma cell proliferation.The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation.The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's DiseaseTranscriptional repression of ER through hMAPK dependent histone deacetylation by class I HDACs.Selective antihypertensive dihydropyridines lower Aβ accumulation by targeting both the production and the clearance of Aβ across the blood-brain barrier.CD40/CD40L interaction induces Abeta production and increases gamma-secretase activity independently of tumor necrosis factor receptor associated factor (TRAF) signaling.CD40 ligation mediates plaque-associated tau phosphorylation in beta-amyloid overproducing mice.CD40 deficiency mitigates Alzheimer's disease pathology in transgenic mouse models.Model of Alzheimer's disease amyloid-beta peptide based on a RNA binding protein.Orphan diseases: state of the drug discovery art.M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memory.Behavioral effects of CD40-CD40L pathway disruption in aged PSAPP mice.Vitamin C sensitizes melanoma to BET inhibitors.Neuropeptide Y Y2 antagonist treated ovariectomized mice exhibit greater bone mineral density.Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study.The granulocyte macrophage colony stimulating factor (GM-CSF) regulates amyloid beta (Abeta) production.Diagnostic utility of APOE, soluble CD40, CD40L, and Abeta1-40 levels in plasma in Alzheimer's disease.An Ultra-High-Throughput Screen for Catalytic Inhibitors of Serine/Threonine Protein Phosphatases Types 1 and 5 (PP1C and PP5C)Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinomaGenomic regulation after CD40 stimulation in microglia: Relevance to Alzheimer's diseasePlasticity of the electric organ discharge waveform of male Brachyhypopomus pinnicaudatus . II. Social effectsInhibition of HDAC3 reverses Alzheimer's disease-related pathologies in vitro and in the 3xTg-AD mouse modelDrug and disease signature integration identifies synergistic combinations in glioblastomaHDAC Inhibitors Induce Expression and Promote Neurite Outgrowth in Human Neural Progenitor Cells-Derived NeuronsA coding and non-coding transcriptomic perspective on the genomics of human metabolic diseaseEnhancement of BDNF Expression and Memory by HDAC Inhibition Requires BET Bromodomain Reader ProteinsPurification of H3 and H4 Histone Proteins and the Quantification of Acetylated Histone Marks in Cells and Brain TissueLongevity-related molecular pathways are subject to midlife "switch" in humansCharacterization of an agonist probe for opioid receptor mu 1 (OPRM1)-opioid receptor delta 1 (OPRD1) heterodimerizationOptimization and characterization of an antagonist for vasopressin 1a (V1a) receptor
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P50
description
hulumtues
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researcher
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wetenschapper
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հետազոտող
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name
Claude-Henry Volmar
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Claude-Henry Volmar
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Claude-Henry Volmar
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Claude-Henry Volmar
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Claude-Henry Volmar
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type
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Claude-Henry Volmar
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Claude-Henry Volmar
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Claude-Henry Volmar
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Claude-Henry Volmar
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Claude-Henry Volmar
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prefLabel
Claude-Henry Volmar
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Claude-Henry Volmar
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Claude-Henry Volmar
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Claude-Henry Volmar
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Claude-Henry Volmar
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P108
P106
P1153
8833910600
P21
P31
P496
0000-0001-9437-051X