about
Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2Exact model reduction of combinatorial reaction networks.Multiscale model of dynamic neuromodulation integrating neuropeptide-induced signaling pathway activity with membrane electrophysiology.Frequency modulation of ERK activation dynamics rewires cell fate.Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma.Personalized Computational Models as BiomarkersPP1 initiates the dephosphorylation of MASTL, triggering mitotic exit and bistability in human cells.Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients.The complexities and versatility of the RAS-to-ERK signalling system in normal and cancer cells.Crosstalk and signaling switches in mitogen-activated protein kinase cascadesPolyubiquitin chain assembly and organization determine the dynamics of protein activation and degradation.Wnt signalling is a bi-directional vulnerability of cancer cells.Control of the G-protein cascade dynamics by GDP dissociation inhibitors.Hippocampal contribution to vector model hypothesis during cue-dependent navigation.Feedback control strategies for spatial navigation revealed by dynamic modelling of learning in the Morris water maze.Impact of measurement noise, experimental design, and estimation methods on Modular Response Analysis based network reconstructionUnderstanding the role of distance, direction and cue salience in an associative model of landmark learning
P50
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P50
description
hulumtues
@sq
researcher
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wetenschapper
@nl
հետազոտող
@hy
name
Dirk Fey
@ast
Dirk Fey
@en
Dirk Fey
@es
Dirk Fey
@nl
Dirk Fey
@sl
type
label
Dirk Fey
@ast
Dirk Fey
@en
Dirk Fey
@es
Dirk Fey
@nl
Dirk Fey
@sl
prefLabel
Dirk Fey
@ast
Dirk Fey
@en
Dirk Fey
@es
Dirk Fey
@nl
Dirk Fey
@sl
P106
P21
P31
P496
0000-0002-5558-0167