about
Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formationDifluoromethanesulfonyl hypervalent iodonium ylides for electrophilic difluoromethylthiolation reactions under copper catalysisSimulation of Human Plasma Concentrations of Thalidomide and Primary 5-Hydroxylated Metabolites Explored with Pharmacokinetic Data in Humanized TK-NOG Mice.In vivo drug interactions of the teratogen thalidomide with midazolam: heterotropic cooperativity of human cytochrome P450 in humanized TK-NOG mice.Assessment of Protein Binding of 5-Hydroxythalidomide Bioactivated in Humanized Mice with Human P450 3A-Chromosome or Hepatocytes by Two-Dimensional Electrophoresis/Accelerator Mass Spectrometry.Shelf-stable electrophilic trifluoromethylating reagents: A brief historical perspective.Synthetic methods for compounds having CF3-S units on carbon by trifluoromethylation, trifluoromethylthiolation, triflylation, and related reactions.Catalytic asymmetric synthesis of enantioenriched heterocycles bearing a C-CF3 stereogenic center.In vivo formation of dihydroxylated and glutathione conjugate metabolites derived from thalidomide and 5-Hydroxythalidomide in humanized TK-NOG mice.Biological evaluation of both enantiomers of fluoro-thalidomide using human myeloma cell line H929 and others.Thalidomide increases human hepatic cytochrome P450 3A enzymes by direct activation of the pregnane X receptor.Synthesis, configurational stability and stereochemical biological evaluations of (S)- and (R)-5-hydroxythalidomides.Regioisomer-Free C 4h β-Tetrakis(tert-butyl)metallo-phthalocyanines: Regioselective Synthesis and Spectral Investigations.DBFOX-Ph/metal complexes: evaluation as catalysts for enantioselective fluorination of 3-(2-arylacetyl)-2-thiazolidinones.Diastereoselective additive trifluoromethylation/halogenation of isoxazole triflones: synthesis of all-carbon-functionalized trifluoromethyl isoxazoline triflonesSynthesis of Phthalocyanines with a Pentafluorosulfanyl Substituent at Peripheral Positions.Organocatalyzed Trifluoromethylation of Ketones and Sulfonyl Fluorides by Fluoroform under a Superbase System.Human cytochrome P450 oxidation of 5-hydroxythalidomide and pomalidomide, an amino analogue of thalidomide.Trifluoroethoxy-Coated Subphthalocyanine affects Trifluoromethylation of Alkenes and Alkynes even under Low-Energy Red-Light Irradiation.2-Diazo-1-phenyl-2-((trifluoromethyl)sulfonyl)ethan-1-one: Another Utility for Electrophilic Trifluoromethylthiolation Reactions.Regioselective 1,4-trifluoromethylation of α,β-unsaturated ketones via a S-(trifluoromethyl)diphenylsulfonium salts/copper system.Cinchona alkaloid catalyzed enantioselective fluorination of allyl silanes, silyl enol ethers, and oxindoles.Cinchona alkaloid/Ti(IV)-catalyzed enantioselective enamine-trifluoropyruvate condensation-cyclization reaction and its application to drug-like heterocycles.Poly[(3-hexylthiophene)-block-(3-semifluoroalkylthiophene)] for polymer solar cells.Fluorothalidomide: a characterization of maternal and developmental toxicity in rabbits and mice.Cinchona alkaloid-catalyzed asymmetric trifluoromethylation of alkynyl ketones with trimethylsilyl trifluoromethane.Human liver microsomal cytochrome P450 3A enzymes involved in thalidomide 5-hydroxylation and formation of a glutathione conjugate.In vivo formation of a glutathione conjugate derived from thalidomide in humanized uPA-NOG mice.Trifluoroethoxy-coating improves the axial ligand substitution of subphthalocyanine.Sterically Demanding Unsymmetrical Diaryl-λ(3)-iodanes for Electrophilic Pentafluorophenylation and an Approach to α-Pentafluorophenyl Carbonyl Compounds with an All-Carbon Stereocenter.Enantioselective Friedel-Crafts reaction of beta-trifluoromethylated acrylates with pyrroles and its application to the synthesis of trifluorinated heliotridane.2-Fluoro-1,3-benzodithiole-1,1,3,3-tetraoxide: a reagent for nucleophilic monofluoromethylation of aldehydes.Copper-catalyzed enantioselective three-component synthesis of optically active propargylamines from aldehydes, amines, and aliphatic alkynes.Synthesis and configurational stability of (S)- and (R)-deuteriothalidomides.Synthesis of fluorinated allenes via palladium-catalyzed monofluoromethylation using FBSM.Corrigendum: Regioisomer-Free C 4h β-Tetrakis(tert-butyl)metallo-phthalocyanines: Regioselective Synthesis and Spectral Investigations.Efficient access to extended Yagupolskii-Umemoto-type reagents: triflic acid catalyzed intramolecular cyclization of ortho-ethynylaryltrifluoromethylsulfanes.Cytotoxic effect of amide derivatives of trifluoromethionine against the enteric protozoan parasite Entamoeba histolytica.Enantioselective electrophilic trifluoromethylation of beta-keto esters with Umemoto reagents induced by chiral nonracemic guanidines.Enantioselective monofluoromethylation of aldehydes with 2-fluoro-1,3-benzodithiole-1,1,3,3-tetraoxide catalyzed by a bifunctional cinchona alkaloid-derived thiourea-titanium complex.
P50
Q27739531-7829B3E5-D8FB-4610-8709-7B20A33EEE9BQ28601782-D2219A30-606C-4145-A614-F7878DC15A4AQ31009764-512FFEBE-813A-4206-BCA8-BDC85C641DA2Q33725370-0A6BEAC5-A12D-474E-9E48-194230B091B0Q37616087-AD5FEE82-2D4A-423F-8E1E-F399022FB280Q37779490-85F204AE-0180-42AF-9B1F-132953B7ACEBQ38239731-A4D2C872-D443-4186-BEF7-C0BDCF3F4950Q38367314-9B40BFDE-12E6-409A-82BD-2E0F759FCD08Q38622206-EDFBDF3E-B9A1-472E-B5D6-94F43D408703Q38649220-F72E5601-1CD7-4A35-BCBD-E787B04D4633Q39031109-1E48BCDB-1803-4702-957E-E20CA450329CQ39871209-9BDBE8ED-ECAB-459A-9E4A-FDCC8962E167Q40298092-247318BE-F822-4CEE-A251-BD8529C57ACEQ40989455-741C676D-7470-4363-848F-FE93BB121152Q41777037-D91EC15C-3B88-4BA2-A15D-06BBAFA4744CQ41791511-69D909DE-BF01-474D-985D-A75DF63F335FQ41828750-9DF881B8-893D-4B4A-AD46-79600FCD256AQ41966805-28A3D1E6-6CAC-4F33-AAAE-B6A160A9545DQ42013837-19D1F44E-D878-46C9-A889-7D9331AEB676Q42150661-A707DDA4-30DA-4D35-B557-2529ABF78EF2Q42154319-452477D6-E0BC-4555-B70B-74B0550A3498Q42163134-A80BF1BD-230A-4DE2-8E2A-9BB2990185F4Q42167336-67F2B818-5097-4D4F-8CBE-F25449DCCAD1Q42733504-15967045-E00A-41BA-BEE9-887F7F8F20F1Q42742389-B1785E1D-B85F-4F6D-A81F-85EE18702143Q42855813-8A32C8AB-C6CA-4E57-836B-6C0AD9F5022FQ42861145-92290AEA-AC95-4727-8B2B-6AFA56934A0BQ42870979-0BB37359-07F2-44B1-AF2E-2E6A03718D70Q43058889-4FD0FF59-D5B2-46A4-AFE9-D2378D824054Q43086626-0D207E56-46C2-487E-98EB-A1D649E2C4C6Q43167377-0A8C3D77-B6FF-48C0-97F0-B219C10075A8Q43179002-E67244CA-4040-4AF2-A77B-5375F04FEC94Q43182204-A5736B02-3DB7-4802-9C30-A5E17704CD04Q43203137-2088541C-5523-46F5-815F-C8B991D2C069Q43213792-C347D6D6-96C9-467A-A4AD-78A6037152F6Q43216669-07B3F0DB-F9C7-4337-8904-5EB0AEAA41B3Q43219010-0A444F6F-C8D7-408A-8EA2-ED855C8A164EQ43243271-B8AA8B18-3900-478B-9425-7C6F3140F427Q43292693-E5CF7AA8-703F-4080-B623-5C8CB85FCF0AQ43416619-2C6DA9DD-B065-42F8-850B-2597CB3E2BCA
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Norio Shibata
@ast
Norio Shibata
@en
Norio Shibata
@es
Norio Shibata
@nl
Norio Shibata
@sl
type
label
Norio Shibata
@ast
Norio Shibata
@en
Norio Shibata
@es
Norio Shibata
@nl
Norio Shibata
@sl
prefLabel
Norio Shibata
@ast
Norio Shibata
@en
Norio Shibata
@es
Norio Shibata
@nl
Norio Shibata
@sl
P106
P1153
7202534160
P21
P31
P3835
norio-shibata
P496
0000-0002-3742-4064
P569
2000-01-01T00:00:00Z