Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol. - Test2 - elhamkhani - TriplyDB

Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol.

Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol.

http://www.wikidata.org/entity/Q41808396

about

The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant.Oral cannabidiol does not produce a signal for abuse liability in frequent marijuana smokers.De novo and inherited SCN8A epilepsy mutations detected by gene panel analysis.Cannabidiol Mellows Out Resurgent Sodium Current Aberrant Sodium Channel Currents and Hyperexcitability of Medial Entorhinal Cortex Neurons in a Mouse Model of SCN8A Encephalopathy.Pro-excitatory alterations in sodium channel activity facilitate subiculum neuron hyperexcitability in temporal lobe epilepsy.Ion Channels in Genetic Epilepsy: From Genes and Mechanisms to Disease-Targeted Therapies.Evaluation of Cannabidiol in Animal Seizure Models by the Epilepsy Therapy Screening Program (ETSP).Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome.Cannabinoids for epilepsy: What do we know and where do we go?Reefer to the Rescue: The Dope on Cannabidiol as a Multi-Symptom Panacea for Dravet Syndrome.Inhibitory effects of cannabidiol on voltage-dependent sodium currents

P2860

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P2860

Aberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol.

http://www.wikidata.org/entity/Q41808396

description

2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

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name

Aberrant epilepsy-associated m ...... be targeted with cannabidiol.

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type

label

Aberrant epilepsy-associated m ...... be targeted with cannabidiol.

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Aberrant epilepsy-associated m ...... be targeted with cannabidiol.

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Aberrant epilepsy-associated m ...... be targeted with cannabidiol.

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Cindy Barbosa

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Nickolay Brustovetsky

http://www.w3.org/2001/XMLSchema#string

Reesha R Patel

http://www.w3.org/2001/XMLSchema#string

Tatiana Brustovetsky

http://www.w3.org/2001/XMLSchema#string

Theodore R Cummins

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P2860

Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2

Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathy

Targeted resequencing in epileptic encephalopathies identifies de novo mutations in CHD2 and SYNGAP1.

Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia

Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system

Single-channel properties of human NaV1.1 and mechanism of channel dysfunction in SCN1A-associated epilepsy

Cannabidiol: pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders

Dopaminergic modulation of striatal neurons, circuits, and assemblies

Resurgent current of voltage-gated Na(+) channels

De novo pathogenic SCN8A mutation identified by whole-genome sequencing of a family quartet affected by infantile epileptic encephalopathy and SUDEP

P304

2164-2181

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scholarly article

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10.1093/BRAIN/AWW129

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P433

Pt 8

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139

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2016-06-05T00:00:00Z

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27267376

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4958898

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