about
Computational models reveal a passive mechanism for cell migration in the cryptChaste: an open source C++ library for computational physiology and biology.A two-dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheathTen simple rules for a successful cross-disciplinary collaborationTen simple rules for effective computational researchOn an infrastructure to support sharing and aggregating pre- and post-publication systems biology research data.Chaste: using agile programming techniques to develop computational biology software.Evaluation of the growth environment of a hydrostatic force bioreactor for preconditioning of tissue-engineered constructsComparing individual-based approaches to modelling the self-organization of multicellular tissuesThe role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt.Mechano-logical model of C. elegans germ line suggests feedback on the cell cycle.Reversible host cell remodeling underpins deformability changes in malaria parasite sexual blood stages.Colorectal cancer through simulation and experiment.Implementing vertex dynamics models of cell populations in biology within a consistent computational framework.On-lattice agent-based simulation of populations of cells within the open-source Chaste framework.The influence of hydrostatic pressure on tissue engineered bone development.Multiscale Model of Colorectal Cancer Using the Cellular Potts Framework.The free energy landscape of dimerization of a membrane protein, NanC.CoGNaC: A Chaste Plugin for the Multiscale Simulation of Gene Regulatory Networks Driving the Spatial Dynamics of Tissues and Cancer.Combined changes in Wnt signaling response and contact inhibition induce altered proliferation in radiation-treated intestinal crypts.Hydrodynamic dispersion within porous biofilms.The interplay between tissue growth and scaffold degradation in engineered tissue constructs.Validity of the Cauchy-Born rule applied to discrete cellular-scale models of biological tissues.Modelling the role of the basement membrane beneath a growing epithelial monolayer.The influence of bioreactor geometry and the mechanical environment on engineered tissues.An integrative computational model for intestinal tissue renewal.A computational study of discrete mechanical tissue models.Connecting Models to Data in Multiscale Multicellular Tissue SimulationsModelling the effect of subcellular mutations on the migration of cells in the colorectal crypt
P50
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P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
James M. Osborne
@ast
James M. Osborne
@en
James M. Osborne
@es
James M. Osborne
@sl
type
label
James M. Osborne
@ast
James M. Osborne
@en
James M. Osborne
@es
James M. Osborne
@sl
prefLabel
James M. Osborne
@ast
James M. Osborne
@en
James M. Osborne
@es
James M. Osborne
@sl
P1053
B-4214-2017
P106
P1153
26768162200
P21
P2456
P31
P3829
P496
0000-0002-5622-0104