Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation.
about
The structure and function of the eukaryotic ribosomeA novel mutation in β integrin reveals an integrin-mediated interaction between the extracellular matrix and cki-1/p27KIP1Mechanism of eIF6-mediated Inhibition of Ribosomal Subunit JoiningCryo-EM Structure of the Archaeal 50S Ribosomal Subunit in Complex with Initiation Factor 6 and Implications for Ribosome EvolutionWorking hard at the nexus between cell signaling and the ribosomal machinery: An insight into the roles of RACK1 in translational regulationThe role of prostate tumor overexpressed 1 in cancer progressionRegulation of translation initiation in eukaryotes: mechanisms and biological targetsEukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species-dependent megakaryocyte maturationRACK1 depletion in a mouse model causes lethality, pigmentation deficits and reduction in protein synthesis efficiencyeIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcriptionActive chemical fractions of stem bark extract of Khaya grandifoliola C.DC and Entada africana Guill. et Perr. synergistically protect primary rat hepatocytes against paracetamol-induced damageeIF5A promotes translation elongation, polysome disassembly and stress granule assemblyTargeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signalingThe pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma.Cyclin K and cyclin D1b are oncogenic in myeloma cells.Sensitivity of global translation to mTOR inhibition in REN cells depends on the equilibrium between eIF4E and 4E-BP1.The cancerous translation apparatusIntegrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate.An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer.Translational control from head to tail.Functional analysis of a novel glioma antigen, EFTUD1.Eukaryotic initiation factor 6, an evolutionarily conserved regulator of ribosome biogenesis and protein translation.EIF6 over-expression increases the motility and invasiveness of cancer cells by modulating the expression of a critical subset of membrane-bound proteinsTranslational regulation in nutrigenomics.Meta-analysis of gene-based genome-wide association studies of bone mineral density in Chinese and European subjects.In Vivo Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Translation Insufficiency.The translation factor eIF6 is a Notch-dependent regulator of cell migration and invasionProteome Differences in Placenta and Endometrium between Normal and Intrauterine Growth Restricted Pig FetusesProteomic and protein interaction network analysis of human T lymphocytes during cell-cycle entryA translation inhibitor identified in a Drosophila screen enhances the effect of ionizing radiation and taxol in mammalian models of cancerThe Role of Translational Regulation in Survival after Radiation Damage; an Opportunity for Proteomics Analysis.Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery diseaseEvolutionary conservation and diversification of the translation initiation apparatus in trypanosomatids.Protective Effects of Scutellarin on Human Cardiac Microvascular Endothelial Cells against Hypoxia-Reoxygenation Injury and Its Possible Target-Related ProteinsSBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention.Genetic removal of p70 S6 kinase 1 corrects molecular, synaptic, and behavioral phenotypes in fragile X syndrome mice.Expression and activity of eIF6 trigger malignant pleural mesothelioma growth in vivo.Translational control in cancer etiology.Degradation of newly synthesized polypeptides by ribosome-associated RACK1/c-Jun N-terminal kinase/eukaryotic elongation factor 1A2 complex.Function and ribosomal localization of aIF6, a translational regulator shared by archaea and eukarya.
P2860
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P2860
Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Eukaryotic initiation factor 6 ...... on, growth and transformation.
@en
type
label
Eukaryotic initiation factor 6 ...... on, growth and transformation.
@en
prefLabel
Eukaryotic initiation factor 6 ...... on, growth and transformation.
@en
P2093
P2860
P356
P1433
P1476
Eukaryotic initiation factor 6 ...... on, growth and transformation.
@en
P2093
Anna Maria Barbieri
Annarita Miluzio
Anne Beugnet
Hiroaki Kiyokawa
Pier Carlo Marchisio
Valentina Gandin
P2860
P2888
P304
P356
10.1038/NATURE07267
P407
P577
2008-09-10T00:00:00Z
P5875
P6179
1025251168