Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation. - Test2 - elhamkhani - TriplyDB

Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation.

Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation.

http://www.wikidata.org/entity/Q41871917

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The structure and function of the eukaryotic ribosome A novel mutation in β integrin reveals an integrin-mediated interaction between the extracellular matrix and cki-1/p27KIP1 Mechanism of eIF6-mediated Inhibition of Ribosomal Subunit Joining Cryo-EM Structure of the Archaeal 50S Ribosomal Subunit in Complex with Initiation Factor 6 and Implications for Ribosome Evolution Working hard at the nexus between cell signaling and the ribosomal machinery: An insight into the roles of RACK1 in translational regulation The role of prostate tumor overexpressed 1 in cancer progression Regulation of translation initiation in eukaryotes: mechanisms and biological targets Eukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species-dependent megakaryocyte maturation RACK1 depletion in a mouse model causes lethality, pigmentation deficits and reduction in protein synthesis efficiency eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription Active chemical fractions of stem bark extract of Khaya grandifoliola C.DC and Entada africana Guill. et Perr. synergistically protect primary rat hepatocytes against paracetamol-induced damage eIF5A promotes translation elongation, polysome disassembly and stress granule assembly Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling The pre-rRNA processing factor DEF is rate limiting for the pathogenesis of MYCN-driven neuroblastoma.Cyclin K and cyclin D1b are oncogenic in myeloma cells.Sensitivity of global translation to mTOR inhibition in REN cells depends on the equilibrium between eIF4E and 4E-BP1.The cancerous translation apparatus Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate.An integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer.Translational control from head to tail.Functional analysis of a novel glioma antigen, EFTUD1.Eukaryotic initiation factor 6, an evolutionarily conserved regulator of ribosome biogenesis and protein translation.EIF6 over-expression increases the motility and invasiveness of cancer cells by modulating the expression of a critical subset of membrane-bound proteins Translational regulation in nutrigenomics.Meta-analysis of gene-based genome-wide association studies of bone mineral density in Chinese and European subjects.In Vivo Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Translation Insufficiency.The translation factor eIF6 is a Notch-dependent regulator of cell migration and invasion Proteome Differences in Placenta and Endometrium between Normal and Intrauterine Growth Restricted Pig Fetuses Proteomic and protein interaction network analysis of human T lymphocytes during cell-cycle entry A translation inhibitor identified in a Drosophila screen enhances the effect of ionizing radiation and taxol in mammalian models of cancer The Role of Translational Regulation in Survival after Radiation Damage; an Opportunity for Proteomics Analysis.Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease Evolutionary conservation and diversification of the translation initiation apparatus in trypanosomatids.Protective Effects of Scutellarin on Human Cardiac Microvascular Endothelial Cells against Hypoxia-Reoxygenation Injury and Its Possible Target-Related Proteins SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention.Genetic removal of p70 S6 kinase 1 corrects molecular, synaptic, and behavioral phenotypes in fragile X syndrome mice.Expression and activity of eIF6 trigger malignant pleural mesothelioma growth in vivo.Translational control in cancer etiology.Degradation of newly synthesized polypeptides by ribosome-associated RACK1/c-Jun N-terminal kinase/eukaryotic elongation factor 1A2 complex.Function and ribosomal localization of aIF6, a translational regulator shared by archaea and eukarya.

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Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation.

http://www.wikidata.org/entity/Q41871917

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2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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name

Eukaryotic initiation factor 6 ...... on, growth and transformation.

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Eukaryotic initiation factor 6 ...... on, growth and transformation.

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Eukaryotic initiation factor 6 ...... on, growth and transformation.

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Eukaryotic initiation factor 6 ...... on, growth and transformation.

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Anna Maria Barbieri

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Annarita Miluzio

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Anne Beugnet

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Hiroaki Kiyokawa

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Pier Carlo Marchisio

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Valentina Gandin

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P2860

Nucleophosmin regulates the stability and transcriptional activity of p53

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

Fibronectin controls cap-dependent translation through beta1 integrin and eukaryotic initiation factors 4 and 2 coordinated pathways

The beta4 integrin interactor p27(BBP/eIF6) is an essential nuclear matrix protein involved in 60S ribosomal subunit assembly

Sen34p depletion blocks tRNA splicing in vivo and delays rRNA processing.

The Saccharomyces cerevisiae TIF6 gene encoding translation initiation factor 6 is required for 60S ribosomal subunit biogenesis.

The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast.

The nucle(ol)ar Tif6p and Efl1p are required for a late cytoplasmic step of ribosome synthesis.

The Saccharomyces cerevisiae homologue of mammalian translation initiation factor 6 does not function as a translation initiation factor.

Cloning of murine translation initiation factor 6 and functional analysis of the homologous sequence YPR016c in Saccharomyces cerevisiae.

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10.1038/NATURE07267

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7213

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455

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1025251168

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18784653

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2753212

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