about
Bioactive indole derivatives from the South Pacific marine sponges Rhopaloeides odorabile and Hyrtios spSynthesis and in vitro and in vivo evaluation of antimalarial polyamines.Chemical and biological explorations of the electrophilic reactivity of the bioactive marine natural product halenaquinone with biomimetic nucleophiles.Investigation of indolglyoxamide and indolacetamide analogues of polyamines as antimalarial and antitrypanosomal agents.Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and photo-dimersChemical discovery and global gene expression analysis in zebrafish.Novel Adociaquinone Derivatives from the Indonesian Sponge Xestospongia sp.Structure-Activity Relationships of the Bioactive Thiazinoquinone Marine Natural Products Thiaplidiaquinones A and B.Biologically Active Acetylenic Amino Alcohol and N-Hydroxylated 1,2,3,4-Tetrahydro-β-carboline Constituents of the New Zealand Ascidian Pseudodistoma opacum.Technology for high-throughput screens: the present and future using zebrafish.Pyrroloiminoquinone and related metabolites from marine sponges.Discovery and preliminary structure-activity relationship studies on tecomaquinone I and tectol as novel farnesyltransferase and plasmodial inhibitors.Natural product growth inhibitors of Mycobacterium tuberculosis.Discovery and evaluation of thiazinoquinones as anti-protozoal agents.Whole organism approaches to chemical genomics: the promising role of zebrafish (Danio rerio).Synthesis and biological evaluation of the ascidian blood-pigment halocyamine A.Structure-activity relationship studies on thiaplidiaquinones A and B as novel inhibitors of Plasmodium falciparum and farnesyltransferase.Synthesis, DNA binding and antitumor evaluation of styelsamine and cystodytin analogues.Synthesis and antimalarial evaluation of artesunate-polyamine and trioxolane-polyamine conjugates.Antimalarial β-carbolines from the New Zealand ascidian Pseudodistoma opacum.Anti-inflammatory and antimalarial meroterpenoids from the New Zealand ascidian Aplidium scabellum.Naamidine A is an antagonist of the epidermal growth factor receptor and an in vivo active antitumor agent.Total synthesis of panicein A2.Enantiomeric 1,2,3-trithiane-containing alkaloids and two new 1,3-dithiane alkaloids from New Zealand ascidians.A new biologically active malyngamide from a New Zealand collection of the sea hare Bursatella leachii.Mechanism of ascididemin-induced cytotoxicity.1,3-dimethyl-8-oxoisoguanine, a new purine from the New Zealand ascidian Pseudodistoma cereum.Enantiomeric discorhabdin alkaloids and establishment of their absolute configurations using theoretical calculations of electronic circular dichroism spectra.Synthesis and anti-inflammatory structure-activity relationships of thiazine-quinoline-quinones: inhibitors of the neutrophil respiratory burst in a model of acute gouty arthritis.Isolation and stereospecific synthesis of janolusimide B from a New Zealand collection of the bryozoan Bugula flabellata.The transcriptional responses of Mycobacterium tuberculosis to inhibitors of metabolism: novel insights into drug mechanisms of action.Efficacy of a series of alpha-pyrone derivatives against Leishmania (L.) infantum and Trypanosoma cruzi.Discovery and preliminary structure-activity relationship analysis of 1,14-sperminediphenylacetamides as potent and selective antimalarial lead compounds.Screening and Biological Effects of Marine Pyrroloiminoquinone Alkaloids: Potential Inhibitors of the HIF-1α/p300 Interaction.Total Synthesis of (-)-Bicubebin A, B, (+)-Bicubebin C and Structural Reassignment of (-)-cis-Cubebin.Identification of heteroarylenamines as a new class of antituberculosis lead molecules.Kottamides A-D: novel bioactive imidazolone-containing alkaloids from the New Zealand ascidian Pycnoclavella kottae.Rossinones A and B, biologically active meroterpenoids from the Antarctic ascidian, Aplidium speciesSemi-synthetic preparation of the rare, cytotoxic, deep-sea sourced sponge metabolites discorhabdins P and UInvestigation of the electrophilic reactivity of the biologically active marine sesquiterpenoid onchidal and model compounds
P50
Q28240786-E89D412C-0341-48C4-9AB6-8210CF70973FQ31135386-3C4C1E9E-6363-4072-A810-1ECD444C5F0FQ33800241-D66DB05B-5A8D-47C9-9B76-51501B1F1AE1Q33808893-4055CACE-9B50-4DB0-B9E2-9D05752002B4Q34143574-FB438B0F-4456-458A-B426-0A6856CE73DBQ35190124-4EE0F426-99F4-454C-933D-050C026E15F9Q35618794-30B0BD64-A47B-4692-8226-BA3348B27C4AQ35743501-40DB559A-0B12-4B96-9846-1BE0BC3A29AFQ35869357-A81B0878-EF1E-4D22-832A-882877E164C6Q35961221-51B2EAED-B434-4FB5-AF61-5EF792FF7BDDQ36030788-F1967F94-E7F7-47CD-9861-848888BB167BQ36033986-F9D18708-77EF-4C4F-8681-400697476068Q36772385-379A7646-DB7F-4F21-B5F0-5C81344CAB16Q37250736-03D3AC23-1100-40D5-93D7-705444F286D0Q38088735-B855E4B1-007D-4886-986A-A543072C5F30Q38369367-04465D49-FAB6-46CF-8E1B-E294AE87498AQ38369600-D4203A36-C3D1-4756-822D-81F0B5F7BA10Q39203079-1441190F-9838-4BD9-AFE4-45B28FFC9B66Q41911790-4B177A80-3C38-4313-9555-014BA0C1350EQ41931966-382B26FE-89F0-4D82-9B71-65A9B2D10F32Q42726502-CF47336F-1857-4AE4-97C7-ABDB14747802Q42826188-FFDB1D53-B549-45FF-911A-5539936E57DEQ43154029-00D25D04-07F2-4DBE-9B0E-ABA726CF97A4Q43808405-38B827E2-077F-41E9-8D49-D45AD846E8E2Q43970629-97214410-1A40-4724-B234-F54FCCFB0443Q44316458-5A4C8F13-6090-4D00-A05A-0294FAA79686Q44770724-A0E6552C-A14D-4E2B-9571-C39019F18FF5Q46316293-09B51E12-BB37-4D5A-9D64-B98A8AF1E282Q46331414-F162B961-C053-4F8B-9663-9D6801343980Q46800395-E86821D7-016F-4A7A-A453-589E44EDF034Q47215316-7C47A8AE-6A6B-4128-A056-3ADFC89A07FFQ48020886-E2CB4B21-72F5-41F6-9C48-CC1A307C021AQ48029436-14150B7F-86E3-4C13-B267-1253208935E9Q51292357-8428C38E-4C48-4C3D-9FD8-0245B63C6F5BQ53075496-D878194C-F5A4-497E-9B74-D80A1AA682EFQ53851471-01F74FF6-96BD-43D1-9DDC-55C090BA0BEEQ54541740-EF00CB3C-8D90-4239-BB46-8FEAECE50BB5Q56949141-ECF0A2CB-9A59-40B2-A587-43B2BBCFE89CQ57087889-11C9AEA4-6148-4B52-857E-6F720B44FACAQ58705070-7BD05FCC-F32B-4CC0-B79C-4AE76B2C4CCC
P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Brent R Copp
@ast
Brent R Copp
@en
Brent R Copp
@es
Brent R Copp
@nl
Brent R Copp
@sl
type
label
Brent R Copp
@ast
Brent R Copp
@en
Brent R Copp
@es
Brent R Copp
@nl
Brent R Copp
@sl
prefLabel
Brent R Copp
@ast
Brent R Copp
@en
Brent R Copp
@es
Brent R Copp
@nl
Brent R Copp
@sl
P1053
D-3706-2009
P106
P21
P31
P3829
P496
0000-0001-5492-5269