The microcephaly protein Asp regulates neuroepithelium morphogenesis by controlling the spatial distribution of myosin II.
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Proliferation control in neural stem and progenitor cellsCell division and the maintenance of epithelial orderInterkinetic nuclear migration generates and opposes ventricular-zone crowding: insight into tissue mechanicsAn Asp-CaM complex is required for centrosome-pole cohesion and centrosome inheritance in neural stem cellsMicrocephaly protein Asp focuses the minus ends of spindle microtubules at the pole and within the spindleLateral adhesion drives reintegration of misplaced cells into epithelial monolayersCdk1 Activates Pre-mitotic Nuclear Envelope Dynein Recruitment and Apical Nuclear Migration in Neural Stem CellsAneuploidy causes premature differentiation of neural and intestinal stem cellsAn integrated platform for large-scale data collection and precise perturbation of live Drosophila embryos.Nuclear envelope: positioning nuclei and organizing synapsesA drosophila genetic resource of mutants to study mechanisms underlying human genetic diseasesMicrocephaly genes evolved adaptively throughout the evolution of eutherian mammalsCenpj/CPAP regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1Distinct molecular cues ensure a robust microtubule-dependent nuclear positioning in the Drosophila oocyteSmall organelle, big responsibility: the role of centrosomes in development and disease.Morphological and functional aspects of progenitors perturbed in cortical malformations.Aspm sustains postnatal cerebellar neurogenesis and medulloblastoma growth in mice.Mutations in KATNB1 cause complex cerebral malformations by disrupting asymmetrically dividing neural progenitorsA challenge of numbers and diversity: neurogenesis in the Drosophila optic lobe.The centrosome duplication cycle in health and disease.The Janus soul of centrosomes: a paradoxical role in disease?ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination.CTP Synthase Is Required for Optic Lobe Homeostasis in Drosophila.Optix defines a neuroepithelial compartment in the optic lobe of the Drosophila brain.WDR81 mutations cause extreme microcephaly and impair mitotic progression in human fibroblasts and Drosophila neural stem cells.Human microcephaly ASPM protein is a spindle pole-focusing factor that functions redundantly with CDK5RAP2.Consequences of Centrosome Dysfunction During Brain Development.Cooperation Between Kinesin Motors Promotes Spindle Symmetry and Chromosome Organization in Oocytes.Pins is not required for spindle orientation in the Drosophila wing disc.Interkinetic nuclear migration in the mouse embryonic ureteric epithelium: Possible implication for congenital anomalies of the kidney and urinary tract.How the spindle keeps its focus.Recapitulating cortical development with organoid culture in vitro and modeling abnormal spindle-like (ASPM related primary) microcephaly disease.Sequential activities of Dynein, Mud and Asp in centrosome-spindle coupling maintain centrosome number upon mitosis.Proteomic Dissection of Nanotopography-Sensitive Mechanotransductive Signaling Hubs that Foster Neuronal Differentiation in PC12 Cells.Same but different: pleiotropy in centrosome-related microcephaly.Live imaging of developing mouse retinal slices
P2860
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P2860
The microcephaly protein Asp regulates neuroepithelium morphogenesis by controlling the spatial distribution of myosin II.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
The microcephaly protein Asp r ...... ial distribution of myosin II.
@en
type
label
The microcephaly protein Asp r ...... ial distribution of myosin II.
@en
prefLabel
The microcephaly protein Asp r ...... ial distribution of myosin II.
@en
P2093
P2860
P356
P1433
P1476
The microcephaly protein Asp r ...... tial distribution of myosin II
@en
P2093
Carole Pennetier
Gaelle le Dez
Maria A Rujano
Renata Basto
P2860
P2888
P304
P356
10.1038/NCB2858
P577
2013-10-20T00:00:00Z