Reduction of endoplasmic reticulum- mitochondria interactions in beta cells from patients with type 2 diabetes.

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Sirolimus induces depletion of intracellular calcium stores and mitochondrial dysfunction in pancreatic beta cells.The role of endoplasmic reticulum-mitochondria contact sites in the control of glucose homeostasis: an update.

P2860

Q45018173-EA016325-41C6-439B-A5EA-B0530D4B4CE6 Q55295690-EDA9CAEE-C1EF-49C4-8A2B-9D01A1809B6A

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Reduction of endoplasmic reticulum- mitochondria interactions in beta cells from patients with type 2 diabetes.

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http://www.wikidata.org/entity/Q42081051

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2017 nî lūn-bûn

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2017年学术文章

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Reduction of endoplasmic retic ...... patients with type 2 diabetes.

@en

Reduction of endoplasmic retic ...... patients with type 2 diabetes.

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type

Item

label

Reduction of endoplasmic retic ...... patients with type 2 diabetes.

@en

Reduction of endoplasmic retic ...... patients with type 2 diabetes.

@nl

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Reduction of endoplasmic retic ...... patients with type 2 diabetes.

@en

Reduction of endoplasmic retic ...... patients with type 2 diabetes.

@nl

P1476

Reduction of endoplasmic retic ...... patients with type 2 diabetes

@en

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Anne-Marie Madec

http://www.w3.org/2001/XMLSchema#string

Romeo Cassel

http://www.w3.org/2001/XMLSchema#string

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Mitochondria-associated endoplasmic reticulum membrane (MAM) integrity is required for insulin signaling and is implicated in hepatic insulin resistance

The different facets of organelle interplay-an overview of organelle interactions

Cell death and survival through the endoplasmic reticulum-mitochondrial axis

Functional characterization of mammalian inositol 1,4,5-trisphosphate receptor isoforms

Further assembly required: construction and dynamics of the endoplasmic reticulum network.

Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol.

Cytochrome c binds to inositol (1,4,5) trisphosphate receptors, amplifying calcium-dependent apoptosis.

Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology.

Subcellular distribution of the inositol 1,4,5-trisphosphate receptors: functional relevance and molecular determinants.

Reduced insulin exocytosis in human pancreatic β-cells with gene variants linked to type 2 diabetes.

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e0182027

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scholarly article

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10.1371/JOURNAL.PONE.0182027

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English

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http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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Jennifer Rieusset

Guillaume Vial

Charles Thivolet

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2017-07-25T00:00:00Z

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28742858

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type-2 diabetes

mitochondrion

endoplasmic reticulum

P932

5526536

http://www.w3.org/2001/XMLSchema#string

Reduction of endoplasmic reticulum- mitochondria interactions in beta cells from patients with type 2 diabetes.

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P2860

P2860

Reduction of endoplasmic reticulum- mitochondria interactions in beta cells from patients with type 2 diabetes.

description

name

type

label

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P1433

P1476

P2093

P2860

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P356

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P698

P921

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P2093

P2860

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P407

P433

P478

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