Genetic analyses of conserved residues in the carboxyl-terminal domain of human immunodeficiency virus type 1 integrase.
about
Posttranslational acetylation of the human immunodeficiency virus type 1 integrase carboxyl-terminal domain is dispensable for viral replicationGene therapy for severe combined immunodeficiency: are we there yet?Primitive hematopoietic cells resist HIV-1 infection via p21Contribution of the C-terminal tri-lysine regions of human immunodeficiency virus type 1 integrase for efficient reverse transcription and viral DNA nuclear importStructural basis for functional tetramerization of lentiviral integraseNon-catalytic site HIV-1 integrase inhibitors disrupt core maturation and induce a reverse transcription block in target cellsRetroviral DNA IntegrationBiochemical and virological analysis of the 18-residue C-terminal tail of HIV-1 integrase.Augmentation of reverse transcription by integrase through an interaction with host factor, SIP1/Gemin2 Is critical for HIV-1 infection.Revealing domain structure through linker-scanning analysis of the murine leukemia virus (MuLV) RNase H and MuLV and human immunodeficiency virus type 1 integrase proteinsCryo-EM structures and atomic model of the HIV-1 strand transfer complex intasomeClathrin facilitates the morphogenesis of retrovirus particles.The HIV-1 integrase mutant R263A/K264A is 2-fold defective for TRN-SR2 binding and viral nuclear import.Non-Enzymatic Functions of Retroviral Integrase: The Next Target for Novel Anti-HIV Drug Development.Comparison Between Several Integrase-defective Lentiviral Vectors Reveals Increased Integration of an HIV Vector Bearing a D167H Mutant.Reverse Transcriptase and Cellular Factors: Regulators of HIV-1 Reverse Transcription.Human immunodeficiency virus type 1 employs the cellular dynein light chain 1 protein for reverse transcription through interaction with its integrase proteinWild-type levels of human immunodeficiency virus type 1 infectivity in the absence of cellular emerin proteinMolecular dynamics approaches estimate the binding energy of HIV-1 integrase inhibitors and correlate with in vitro activity.In Silico and In Vitro Comparison of HIV-1 Subtypes B and CRF02_AG Integrases Susceptibility to Integrase Strand Transfer Inhibitors.Characterization of HIV-1 integrase N-terminal mutant viruses.Interaction between Reverse Transcriptase and Integrase Is Required for Reverse Transcription during HIV-1 Replication.Identification of residues in the C-terminal domain of HIV-1 integrase that mediate binding to the transportin-SR2 protein.Gag-processing defect of human immunodeficiency virus type 1 integrase E246 and G247 mutants is caused by activation of an overlapping 5' splice siteIdentifying and characterizing a functional HIV-1 reverse transcriptase-binding site on integrase.Critical Contribution of Tyr15 in the HIV-1 Integrase (IN) in Facilitating IN Assembly and Nonenzymatic Function through the IN Precursor Form with Reverse Transcriptase.Natural single-nucleotide polymorphisms in the 3' region of the HIV-1 pol gene modulate viral replication ability.Novel integrase inhibitors for HIV.Second generation imaging of nuclear/cytoplasmic HIV-1 complexesSequential deletion of the integrase (Gag-Pol) carboxyl terminus reveals distinct phenotypic classes of defective HIV-1.Identification and characterization of persistent intracellular human immunodeficiency virus type 1 integrase strand transfer inhibitor activityAllosteric HIV-1 Integrase Inhibitors Lead to Premature Degradation of the Viral RNA Genome and Integrase in Target Cells.Correlation of recombinant integrase activity and functional preintegration complex formation during acute infection by replication-defective integrase mutant human immunodeficiency virus.Computational design of a full-length model of HIV-1 integrase: modeling of new inhibitors and comparison of their calculated binding energies with those previously studied.Natural variation of HIV-1 group M integrase: implications for a new class of antiretroviral inhibitors.Lys-34, dispensable for integrase catalysis, is required for preintegration complex function and human immunodeficiency virus type 1 replication.Interaction of human immunodeficiency virus type 1 integrase with cellular nuclear import receptor importin 7 and its impact on viral replication.Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails.Natural polymorphisms of HIV-1 subtype-C integrase coding region in a large group of ARV-naïve infected individuals.CLIP-related methodologies and their application to retrovirology.
P2860
Q24672416-9DAEA4E8-1B50-44A5-9DFB-4BC1C1E9F830Q24680426-B550A360-3F72-42B6-B76B-E04D2ADBE9E3Q24681819-B2482AD4-2949-4DDD-A491-6884D205C1CAQ24814060-1598124F-7D97-4108-BC9D-DDDD1C5EFC8AQ27316560-25C0E8DA-35D9-4ABA-880F-CB9494CFE690Q28536951-CE39CAF2-97F1-46DF-A9FA-5D2B058938C7Q28596842-E3D0764F-AE19-490B-9E8A-0246B7EF1188Q30157084-535CFBDB-F0C0-48DE-8115-AA6D5BDF1F6BQ30885857-4921B979-BE5C-4D5C-8E49-F4C8CAFA47E3Q33257614-446D35B3-1BC2-48B9-A760-BFCD18CCAD2EQ33900890-68D1D1B3-EB01-4AC9-AF3B-01AB4939E80EQ33954411-1288DB6A-9F5A-4F58-A14B-FEA2D0ABC692Q34139212-4F4B98CA-94E4-4EF6-BE7A-58C4DEA3FEFAQ34226132-ACFB3F86-D014-4B78-85FB-E44DF54C7F33Q34745316-A688F201-84BC-462B-89B4-869DB75C773BQ35260021-79FE6D55-2D5A-488B-9B3D-C8B3D7CD5724Q35487739-6C4429BC-1263-4646-BD96-FEFF1516FB06Q35634356-00F7B3FE-10BB-47A1-A09C-A38227A1C2C7Q35666439-F8B0397A-0157-4629-BF76-51536F3C2986Q36099861-55D7C8B2-FADF-4B64-BC48-FDAEA915CAAEQ36169613-444B58E0-A880-437E-8E02-B9234597587EQ36281118-28E733E0-1538-47C0-B517-9C2F9459F292Q36298318-60AF7E98-3CE5-4F74-A22F-4E9BEA546BFFQ36424150-1937189F-BAA7-4924-BB7C-49705290B662Q37134432-31AC0127-5F3C-4B96-8C04-B98EA48F53C9Q37512925-92ECABC3-030B-4E8E-B5F0-B84F6A373A23Q37713854-29A582B4-B297-478B-A20D-EA6EB00FBEFEQ37779774-66B6C0EA-89EB-454C-9B78-88CE1DC29CE4Q38998244-D709BAFD-635C-4B00-B84F-DACFD642BE49Q39582953-03989EB1-2A86-4F07-8318-DF066DDE0BC8Q39634357-972C9FDD-F30F-4E70-90E4-B51FD92CBD5EQ40159851-EC0542EA-03FB-4AB2-A01B-171DEC9876C6Q41841102-244A9691-8673-47F1-B74D-B54011DDFC1FQ42279698-E2078BED-9EDC-4249-A3D2-53BACC667F11Q42746719-AC44602C-53BF-495E-95EC-D59553FF69B5Q42971850-FFBD7A6A-B3AC-4C03-93A5-96DA0D1C7A97Q45406234-4C8C6BFB-2F4E-47CC-8473-3D8BCA2F44A4Q47109194-DF2026F4-FBDF-4290-BC8E-0F615F607A26Q51039642-082ACE31-BE9E-48BA-9087-3BE12E89322DQ54223780-2D4607B1-F79D-4E03-A816-EC974B11E3F2
P2860
Genetic analyses of conserved residues in the carboxyl-terminal domain of human immunodeficiency virus type 1 integrase.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Genetic analyses of conserved ...... ciency virus type 1 integrase.
@en
Genetic analyses of conserved ...... ciency virus type 1 integrase.
@nl
type
label
Genetic analyses of conserved ...... ciency virus type 1 integrase.
@en
Genetic analyses of conserved ...... ciency virus type 1 integrase.
@nl
prefLabel
Genetic analyses of conserved ...... ciency virus type 1 integrase.
@en
Genetic analyses of conserved ...... ciency virus type 1 integrase.
@nl
P2093
P2860
P1433
P1476
Genetic analyses of conserved ...... ciency virus type 1 integrase.
@en
P2093
Alan Engelman
Hina Z Ghory
Richard Lu
P2860
P304
10356-10368
P356
10.1128/JVI.79.16.10356-10368.2005
P407
P577
2005-08-01T00:00:00Z