Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells
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Mechanistic insights into mode of action of novel natural cathepsin L inhibitors.Vasostatin inhibits VEGF-induced endothelial cell proliferation, tube formation and induces cell apoptosis under oxygen deprivation.Microvascular rarefaction: the decline and fall of blood vesselsPhospholipase Cgamma activation drives increased production of autotaxin in endothelial cells and lysophosphatidic acid-dependent regression.Is renal function associated with early age-related macular degeneration?The fat body transcriptomes of the yellow fever mosquito Aedes aegypti, pre- and post- blood mealRhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis.A possible contribution of altered cathepsin B expression to the development of skin sclerosis and vasculopathy in systemic sclerosisCharacterization of thimet oligopeptidase and neurolysin activities in B16F10-Nex2 tumor cells and their involvement in angiogenesis and tumor growth.Cathepsin B and uPAR knockdown inhibits tumor-induced angiogenesis by modulating VEGF expression in gliomaRegulation of cysteine cathepsin expression by oxidative stress in the retinal pigment epithelium/choroid of the mouse.Insulin-like growth factor 1 (IGF-1) stabilizes nascent blood vesselsDiabetes disrupts the response of retinal endothelial cells to the angiomodulator lysophosphatidic acidMEF2C ablation in endothelial cells reduces retinal vessel loss and suppresses pathologic retinal neovascularization in oxygen-induced retinopathyPrimary human endothelial cells secrete agents that reduce responsiveness to lysophosphatidic acid (LPA).Serum Cystatin C, Markers of Chronic Kidney Disease, and Retinopathy in Persons with DiabetesCorticotropin Releasing Hormone and Urocortin 3 Stimulate Vascular Endothelial Growth Factor Expression through the cAMP/CREB Pathway.Nrf2 in ischemic neurons promotes retinal vascular regeneration through regulation of semaphorin 6A.IGFBP-4 anti-angiogenic and anti-tumorigenic effects are associated with anti-cathepsin B activity.Age-related macular degeneration-associated silent polymorphisms in HtrA1 impair its ability to antagonize insulin-like growth factor 1.Role of the retinal vascular endothelial cell in ocular diseaseInduction of vascular atrophy as a novel approach to treating restenosis. A reviewRegression activity that is naturally present in vitreous becomes ineffective as patients develop proliferative diabetic retinopathyMatrix metalloproteinase-1 promotes breast cancer angiogenesis and osteolysis in a novel in vivo modelLactate engages receptor tyrosine kinases Axl, Tie2, and vascular endothelial growth factor receptor 2 to activate phosphoinositide 3-kinase/Akt and promote angiogenesis.Live-cell imaging demonstrates extracellular matrix degradation in association with active cathepsin B in caveolae of endothelial cells during tube formation.Role of cysteine cathepsins in matrix degradation and cell signalling.The transforming growth factor-beta pathway is a common target of drugs that prevent experimental diabetic retinopathySerum cystatin C level, kidney disease markers, and incidence of age-related macular degeneration: the Beaver Dam Eye Study.The angiogenic effect of probiotic Bacillus polyfermenticus on human intestinal microvascular endothelial cells is mediated by IL-8.Editing VEGFR2 Blocks VEGF-Induced Activation of Akt and Tube Formation.In vitro and ex vivo retina angiogenesis assays.Inhibition of pathological retinal angiogenesis by the integrin αvβ3 antagonist tetraiodothyroacetic acid (tetrac).Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma.The neurotensin-HIF-1α-VEGFα axis orchestrates hypoxia, colonic inflammation, and intestinal angiogenesis.Interleukin-12 inhibits pathological neovascularization in mouse model of oxygen-induced retinopathy.Insulin-like growth factor II receptor-mediated intracellular retention of cathepsin B is essential for transformation of endothelial cells by Kaposi's sarcoma-associated herpesvirus.Regulating angiogenesis at the level of PtdIns-4,5-P2.Raised maternal serum cystatin C: an early pregnancy marker for preeclampsia.Angiogenic response of rat hippocampal vasculature to focused ultrasound-mediated increases in blood-brain barrier permeability
P2860
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P2860
Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells
@en
Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells
@nl
type
label
Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells
@en
Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells
@nl
prefLabel
Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells
@en
Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells
@nl
P2093
P2860
P356
P1476
Cathepsin B regulates the intrinsic angiogenic threshold of endothelial cells
@en
P2093
Andrius Kazlauskas
Annapurna Venkatakrishnan
P2860
P304
P356
10.1091/MBC.E04-11-1029
P577
2005-05-18T00:00:00Z