Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination.
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Coupling between catalytic site and collective dynamics: a requirement for mechanochemical activity of enzymesCrystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cellsThe crystal structure of D-lactate dehydrogenase, a peripheral membrane respiratory enzymeCharting a Path to Success in Virtual ScreeningHepatitis C virus NS4B carboxy terminal domain is a membrane binding domainExpression, assay, and structure of the extracellular domain of murine carbonic anhydrase XIV: implications for selective inhibition of membrane-associated isozymesStructural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and IIStructural and catalytic characterization of a thermally stable and acid-stable variant of human carbonic anhydrase II containing an engineered disulfide bondA dynamic C-terminal segment in the Mycobacterium tuberculosis Mn/Fe R2lox protein can adopt a helical structure with possible functional consequencesComputational modeling of laminin N-terminal domains using sparse distance constraints from disulfide bonds and chemical cross-linkingA comparison of the long-term effects of dorzolamide 2% and brinzolamide 1%, each added to timolol 0.5%, on retrobulbar hemodynamics and intraocular pressure in open-angle glaucoma patientsPurification and kinetic analysis of recombinant CA XII, a membrane carbonic anhydrase overexpressed in certain cancers.Ultrahigh resolution crystal structures of human carbonic anhydrases I and II complexed with "two-prong" inhibitors reveal the molecular basis of high affinity.Carbonic anhydrase as a model for biophysical and physical-organic studies of proteins and protein-ligand binding.Update and critical appraisal of combined timolol and carbonic anhydrase inhibitors and the effect on ocular blood flow in glaucoma patients.Structural analysis of inhibitor binding to human carbonic anhydrase IICreation of nano eye-drops and effective drug delivery to the interior of the eye.Testing the limits of sensitivity in a solid-state structural investigation by combined X-ray powder diffraction, solid-state NMR, and molecular modelling.
P2860
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P2860
Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: molecular basis of isozyme-drug discrimination.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Structures of murine carbonic ...... f isozyme-drug discrimination.
@en
Structures of murine carbonic ...... f isozyme-drug discrimination.
@nl
type
label
Structures of murine carbonic ...... f isozyme-drug discrimination.
@en
Structures of murine carbonic ...... f isozyme-drug discrimination.
@nl
prefLabel
Structures of murine carbonic ...... f isozyme-drug discrimination.
@en
Structures of murine carbonic ...... f isozyme-drug discrimination.
@nl
P2093
P2860
P356
P1433
P1476
Structures of murine carbonic ...... f isozyme-drug discrimination.
@en
P2093
D N Silverman
D W Christianson
P A Boriack-Sjodin
P2860
P304
P356
10.1002/PRO.5560070303
P577
1998-03-01T00:00:00Z