about
Highly Selective Phosphatidylinositol 4-Kinase IIIβ Inhibitors and Structural Insight into Their Mode of ActionAnthracycline toxicity to cardiomyocytes or cancer cells is differently affected by iron chelation with salicylaldehyde isonicotinoyl hydrazone.Synthesis of novel purine-based coxsackievirus inhibitors bearing polycylic substituents at the N-9 position.New iron chelators in anthracycline-induced cardiotoxicity.Design and Synthesis of Fluorescent Acyclic Nucleoside Phosphonates as Potent Inhibitors of Bacterial Adenylate Cyclases.Transport mechanisms of a novel antileukemic and antiviral compound 9-norbornyl-6-chloropurine.Amidate prodrugs of 9-[2-(phosphonomethoxy)ethyl]adenine as inhibitors of adenylate cyclase toxin from Bordetella pertussis.Involvement of MAP kinases in the cytotoxicity of acyclic nucleoside phosphonates.Determination of the antioxidative activity of substituted 5-aminopyrimidines.In vivo and in vitro assessment of the role of glutathione antioxidant system in anthracycline-induced cardiotoxicity.Role of caspases and CD95/Fas in the apoptotic effects of a nucleotide analog PMEG in CCRF-CEM cells.Distinct modulation of telomere length in two T-lymphoblastic leukemia cell lines by cytotoxic nucleoside phosphonates PMEG and PMEDAP.Cardioprotective effects of a novel iron chelator, pyridoxal 2-chlorobenzoyl hydrazone, in the rabbit model of daunorubicin-induced cardiotoxicity.2´-deoxy-5,6-dihydro-5-azacytidine - a less toxic alternative of 2´-deoxy-5-azacytidine: a comparative study of hypomethylating potential.SAR studies of 9-norbornylpurines as Coxsackievirus B3 inhibitors.The effect of new lipophilic chelators on the activities of cytosolic reductases and P450 cytochromes involved in the metabolism of anthracycline antibiotics: studies in vitro.Point mutations in human guanylate kinase account for acquired resistance to anticancer nucleotide analogue PMEG.Compound instability in dimethyl sulphoxide, case studies with 5-aminopyrimidines and the implications for compound storage and screening.9-Norbornyl-6-chloropurine is a novel antileukemic compound interacting with cellular GSH.Synthesis of α-branched acyclic nucleoside phosphonates as potential inhibitors of bacterial adenylate cyclases.
P50
Q27700228-7806D13A-B01F-46E1-8B0C-0629C73B8300Q33341069-B2806DD6-F10C-4537-8E04-A1CFA0274083Q35126871-16CCE030-DBDC-4BB0-9B32-C80F7761A29CQ36891765-52102AC6-165C-4186-A586-46782FA53659Q38806723-4159E80C-6860-4355-B288-17C407530A82Q39010597-4CEF11D8-C002-4A49-9DFC-8778BA152798Q39074891-B69870B5-A284-4321-9B01-39957948DF5CQ39404534-846C9B2F-B830-418A-AD1F-D5250F369C02Q39447056-65BC9EE2-8954-43BD-9EE9-B158ECAB9A07Q39636367-F6E3B59B-C1C4-45D7-82C6-B25F3C4A2E20Q39671774-FC636E32-8A8B-49E5-81ED-BDC9902EC34EQ39685001-3A4CBE12-607B-4DA8-99CB-C405A771451AQ40227326-7D561D20-2848-4CE2-8829-AE7F24A857F6Q42838462-5AAC8043-D188-4EE7-8E6B-2C617539ABEFQ43991120-8675F437-F872-4C05-8A6D-021ADC835D7DQ45180010-FFF61494-67B0-48DC-A8D6-0FE300FB5557Q45347064-9F519142-F5C1-4E95-8D98-A867B5AFDDF5Q45383606-70A57374-CD3E-45F8-A283-7C6740C452B9Q46000659-F67F5781-28B7-4137-9DEF-BA7F24EC6185Q46242316-2147BCB6-8F97-4307-AB67-F99F605BEB09
P50
description
Czech biochemist
@en
bithchemiceoir Seiceach
@ga
científica checa
@ast
científica checa
@es
wetenschapster uit Tsjechië
@nl
česká biochemička a farmaceutka
@cs
name
Helena Mertlíková-Kaiserová
@ast
Helena Mertlíková-Kaiserová
@cs
Helena Mertlíková-Kaiserová
@cy
Helena Mertlíková-Kaiserová
@en
Helena Mertlíková-Kaiserová
@es
Helena Mertlíková-Kaiserová
@fr
Helena Mertlíková-Kaiserová
@ga
Helena Mertlíková-Kaiserová
@nl
Helena Mertlíková-Kaiserová
@sl
type
label
Helena Mertlíková-Kaiserová
@ast
Helena Mertlíková-Kaiserová
@cs
Helena Mertlíková-Kaiserová
@cy
Helena Mertlíková-Kaiserová
@en
Helena Mertlíková-Kaiserová
@es
Helena Mertlíková-Kaiserová
@fr
Helena Mertlíková-Kaiserová
@ga
Helena Mertlíková-Kaiserová
@nl
Helena Mertlíková-Kaiserová
@sl
altLabel
Helena Kaiserová
@cs
Helena Mertlikova-Kaiserova
@en
Helena Mertlíková
@cs
prefLabel
Helena Mertlíková-Kaiserová
@ast
Helena Mertlíková-Kaiserová
@cs
Helena Mertlíková-Kaiserová
@cy
Helena Mertlíková-Kaiserová
@en
Helena Mertlíková-Kaiserová
@es
Helena Mertlíková-Kaiserová
@fr
Helena Mertlíková-Kaiserová
@ga
Helena Mertlíková-Kaiserová
@nl
Helena Mertlíková-Kaiserová
@sl
P214
P106
P21
P213
0000 0003 5572 3655
P214
P31
P569
1979-01-01T00:00:00Z