FMNL2 drives actin-based protrusion and migration downstream of Cdc42.
about
Alterations of the apical junctional complex and actin cytoskeleton and their role in colorectal cancer progressionFormins at a glanceCell type-dependent mechanisms for formin-mediated assembly of filopodia.α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3.Junctional actin assembly is mediated by Formin-like 2 downstream of Rac1.Functional hierarchy of redundant actin assembly factors revealed by fine-grained registration of intrinsic image fluctuations.Formin and capping protein together embrace the actin filament in a ménage à trois.Ligand-induced activation of a formin-NPF pair leads to collaborative actin nucleationWAVE binds Ena/VASP for enhanced Arp2/3 complex-based actin assembly.The formins FMNL1 and mDia1 regulate coiling phagocytosis of Borrelia burgdorferi by primary human macrophages.Optical control of protein activity by fluorescent protein domains.The F-BAR protein Cip4/Toca-1 antagonizes the formin Diaphanous in membrane stabilization and compartmentalization.Arp2/3 complex is essential for actin network treadmilling as well as for targeting of capping protein and cofilin.The formin FHOD1 and the small GTPase Rac1 promote vaccinia virus actin-based motility.Ena/VASP Enabled is a highly processive actin polymerase tailored to self-assemble parallel-bundled F-actin networks with FascinNew single-molecule speckle microscopy reveals modification of the retrograde actin flow by focal adhesions at nanometer scales.The formin FMNL3 assembles plasma membrane protrusions that participate in cell-cell adhesion.FMNL formins boost lamellipodial force generation.Myristoylation: An Important Protein Modification in the Immune ResponseCharacterization of Leukocyte Formin FMNL1 Expression in Human Tissues.VEZT, a novel putative tumor suppressor, suppresses the growth and tumorigenicity of gastric cancer.Novel roles for actin in mitochondrial fissionMetastasis suppressor microRNA-335 targets the formin family of actin nucleators.Two functionally distinct sources of actin monomers supply the leading edge of lamellipodiaA specific FMNL2 isoform is up-regulated in invasive cellsEmergence of an Apical Epithelial Cell Surface In VivoComparative gene expression analysis of the fmnl family of formins during zebrafish development and implications for tissue specific functions.Unique and Overlapping Functions of Formins Frl and DAAM During Ommatidial Rotation and Neuronal Development in DrosophilaFMNL2/FMNL3 formins are linked with oncogenic pathways and predict melanoma outcome.ARP2/3-dependent growth in the plant kingdom: SCARs for life.A Diaphanous-related formin links Ras signaling directly to actin assembly in macropinocytosis and phagocytosis.A role for myosin II in mammalian mitochondrial fission.New insights into the regulation and cellular functions of the ARP2/3 complex.RhoA, RhoB and RhoC have different roles in cancer cell migration.Small Rho GTPases in the control of cell shape and mobility.Actin dynamics, architecture, and mechanics in cell motility.Transcriptomic network support distinct roles of classical and non-classical monocytes in human.Bacterial subversion of host cytoskeletal machinery: hijacking formins and the Arp2/3 complex.Formins as effector proteins of Rho GTPasesSelf-organization of protrusions and polarity during eukaryotic chemotaxis.
P2860
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P2860
FMNL2 drives actin-based protrusion and migration downstream of Cdc42.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
FMNL2 drives actin-based protrusion and migration downstream of Cdc42.
@en
FMNL2 drives actin-based protrusion and migration downstream of Cdc42.
@nl
type
label
FMNL2 drives actin-based protrusion and migration downstream of Cdc42.
@en
FMNL2 drives actin-based protrusion and migration downstream of Cdc42.
@nl
prefLabel
FMNL2 drives actin-based protrusion and migration downstream of Cdc42.
@en
FMNL2 drives actin-based protrusion and migration downstream of Cdc42.
@nl
P2093
P2860
P50
P1433
P1476
FMNL2 drives actin-based protrusion and migration downstream of Cdc42
@en
P2093
Dennis Breitsprecher
Jennifer Block
Moritz Winterhoff
Patrick Duwe
Robert Geffers
Sonja Kühn
P2860
P304
P356
10.1016/J.CUB.2012.03.064
P407
P577
2012-05-17T00:00:00Z